6P5I

Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1)

This is a large structure.

Summary for 6P5I

Related6P4G 6P4H
EMDB information20248 20249 20255
Descriptor18S rRNA, uS2, eS1, ... (81 entities in total)
Functional Keywordsisraeli acute paralysis virus, internal ribosome entry site, ires, small ribosomal subunit, 40s, large ribosomal subunit, 60s, 80s, ribosome
Biological sourceIsraeli acute paralysis virus
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Total number of polymer chains81
Total molecular weight3411882.11
Authors
Acosta-Reyes, F.J.,Neupane, R.,Frank, J.,Fernandez, I.S. (deposition date: 2019-05-30, release date: 2019-09-18)
Primary citation
Acosta-Reyes, F.J.,Neupane, R.,Frank, J.,Fernandez, I.S.
The Israeli Acute Paralysis Virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs
to be published,
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone3 0.5% 3.2% 0.45MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures