1Z9E
| Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 | 分子名称: | PC4 and SFRS1 interacting protein 2 | 著者 | Cherepanov, P, Sun, Z.-Y.J, Rahman, S, Maertens, G, Wagner, G, Engelman, A. | 登録日 | 2005-04-01 | 公開日 | 2005-05-17 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 Nat.Struct.Mol.Biol., 12, 2005
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2B4J
| Structural basis for the recognition between HIV-1 integrase and LEDGF/p75 | 分子名称: | GLYCEROL, Integrase (IN), PC4 and SFRS1 interacting protein, ... | 著者 | Cherepanov, P, Ambrosio, A.L, Rahman, S, Ellenberger, T, Engelman, A. | 登録日 | 2005-09-24 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 Proc.Natl.Acad.Sci.Usa, 102, 2005
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1ITG
| CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES | 分子名称: | CACODYLATE ION, HIV-1 INTEGRASE | 著者 | Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R. | 登録日 | 1994-11-21 | 公開日 | 1995-05-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science, 266, 1994
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5D7U
| Crystal structure of the C-terminal domain of MMTV integrase | 分子名称: | ISOPROPYL ALCOHOL, Pr160 | 著者 | Cook, N.J, Pye, V.E, Ballandras-Colas, A, Engelman, A, Cherepanov, P. | 登録日 | 2015-08-14 | 公開日 | 2016-02-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530, 2016
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5CZ2
| Crystal structure of a two-domain fragment of MMTV integrase | 分子名称: | MAGNESIUM ION, Pol polyprotein, ZINC ION | 著者 | Cook, N, Ballandras-Colas, A, Engelman, A, Cherepanov, P. | 登録日 | 2015-07-31 | 公開日 | 2016-02-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530, 2016
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5CZ1
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4WHJ
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3L2Q
| Crystal structure of the Prototype Foamy Virus (PFV) intasome in apo form | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', GLYCEROL, ... | 著者 | Hare, S, Gupta, S.S, Cherepanov, P. | 登録日 | 2009-12-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
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3L2R
| Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ... | 著者 | Hare, S, Gupta, S.S, Cherepanov, P. | 登録日 | 2009-12-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
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3L2U
| Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and GS9137 (Elvitegravir) | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', 6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, ... | 著者 | Hare, S, Gupta, S.S, Cherepanov, P. | 登録日 | 2009-12-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
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3L2V
| Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518 (Raltegravir) | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ... | 著者 | Hare, S, Gupta, S.S, Cherepanov, P. | 登録日 | 2009-12-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
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3OY9
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3F9K
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4TSX
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4JLH
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4GW6
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4GVM
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4ID1
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3HPG
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3HPH
| Closed tetramer of Visna virus integrase (residues 1-219) in complex with LEDGF IBD | 分子名称: | GLYCEROL, Integrase, PC4 and SFRS1-interacting protein, ... | 著者 | Hare, S, Wang, J, Cherepanov, P. | 登録日 | 2009-06-04 | 公開日 | 2009-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis for functional tetramerization of lentiviral integrase Plos Pathog., 5, 2009
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4C0O
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4C0P
| Unliganded Transportin 3 | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TRANSPORTIN-3 | 著者 | Maertens, G.N, Cook, N.J, Hare, S, Cherepanov, P. | 登録日 | 2013-08-06 | 公開日 | 2014-01-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Basis for Nuclear Import of Splicing Factors by Human Transportin 3. Proc.Natl.Acad.Sci.USA, 111, 2014
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4DMN
| HIV-1 Integrase Catalytical Core Domain | 分子名称: | (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, ARSENIC, HIV-1 Integrase, ... | 著者 | Feng, L, Kvaratskhelia, M. | 登録日 | 2012-02-08 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors. J.Biol.Chem., 287, 2012
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4C0Q
| Transportin 3 in complex with Ran(Q69L)GTP | 分子名称: | GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Maertens, G, Hare, S, Cherepanov, P. | 登録日 | 2013-08-06 | 公開日 | 2014-01-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Structural Basis for Nuclear Import of Splicing Factors by Human Transportin 3. Proc.Natl.Acad.Sci.USA, 111, 2014
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1IHV
| SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | HIV-1 INTEGRASE | 著者 | Clore, G.M, Lodi, P.J, Ernst, J.A, Gronenborn, A.M. | 登録日 | 1995-05-12 | 公開日 | 1996-10-14 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the DNA binding domain of HIV-1 integrase. Biochemistry, 34, 1995
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