3OY9
Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese at 2.55 resolution
Replaces: 3L2SSummary for 3OY9
Entry DOI | 10.2210/pdb3oy9/pdb |
Related | 3DLR 3L2Q 3L2R 3L2U 3L2V 3L2W 3OYA 3OYB 3OYC 3OYD 3OYE 3OYF 3OYG 3OYH 3OYI 3OYJ 3OYK 3OYL 3OYM 3OYN |
Descriptor | PFV integrase, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... (9 entities in total) |
Functional Keywords | protein-dna complex, tetramer, dna integration, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, viral nucleoprotein, virion, dna-binding, zinc binding, hhcc motif, viral protein, recombination, dna-binding protein-dna complex, viral protein-dna complex, viral protein/dna |
Biological source | Human spumaretrovirus (SFVcpz(hu)) More |
Cellular location | Integrase: Virion . Protease/Reverse transcriptase/ribonuclease H: Host nucleus : P14350 |
Total number of polymer chains | 4 |
Total formula weight | 100752.35 |
Authors | Hare, S.,Cherepanov, P. (deposition date: 2010-09-23, release date: 2010-10-20, Last modification date: 2023-09-06) |
Primary citation | Hare, S.,Gupta, S.S.,Valkov, E.,Engelman, A.,Cherepanov, P. Retroviral intasome assembly and inhibition of DNA strand transfer. Nature, 464:232-236, 2010 Cited by PubMed: 20118915DOI: 10.1038/nature08784 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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