5CZ2
Crystal structure of a two-domain fragment of MMTV integrase
Summary for 5CZ2
Entry DOI | 10.2210/pdb5cz2/pdb |
Descriptor | Pol polyprotein, MAGNESIUM ION, ZINC ION (3 entities in total) |
Functional Keywords | integrase, pol, retrovirus, amino terminal domain, catalytic core domain, zinc binding, hydrolase |
Biological source | Mouse mammary tumor virus (strain BR6) (MMTV) |
Total number of polymer chains | 12 |
Total formula weight | 286955.76 |
Authors | Cook, N.,Ballandras-Colas, A.,Engelman, A.,Cherepanov, P. (deposition date: 2015-07-31, release date: 2016-02-17, Last modification date: 2024-01-10) |
Primary citation | Ballandras-Colas, A.,Brown, M.,Cook, N.J.,Dewdney, T.G.,Demeler, B.,Cherepanov, P.,Lyumkis, D.,Engelman, A.N. Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530:358-361, 2016 Cited by PubMed: 26887496DOI: 10.1038/nature16955 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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