5CZ1

Crystal structure of the catalytic core domain of MMTV integrase

Summary for 5CZ1

Entry DOI	10.2210/pdb5cz1/pdb
Descriptor	integrase (2 entities in total)
Functional Keywords	integrase, pol, retrovirus, catalytic core domain, hydrolase
Biological source	Mouse mammary tumor virus (MMTV)
Total number of polymer chains	4
Total formula weight	77240.42
Authors	Cook, N.,Ballandras-Colas, A.,Engelman, A.,Cherepanov, P. (deposition date: 2015-07-31, release date: 2016-02-17, Last modification date: 2024-01-10)
Primary citation	Ballandras-Colas, A.,Brown, M.,Cook, N.J.,Dewdney, T.G.,Demeler, B.,Cherepanov, P.,Lyumkis, D.,Engelman, A.N. Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530:358-361, 2016 Cited by PubMed: 26887496 DOI: 10.1038/nature16955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation