Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4AL7
DownloadVisualize
BU of 4al7 by Molmil
Crystal structure of the Csy4-minimal crRNA complex
分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*AP*G)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4CMP
DownloadVisualize
BU of 4cmp by Molmil
Crystal structure of S. pyogenes Cas9
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION
著者Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
登録日2014-01-16
公開日2014-02-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
4AN8
DownloadVisualize
BU of 4an8 by Molmil
Structure of Thermus thermophilus CasA (Cse1)
分子名称: ACETATE ION, CSE1
著者Sashital, D.G, Wiedenheft, B, Doudna, J.A.
登録日2012-03-16
公開日2012-05-02
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System.
Mol.Cell, 46, 2012
4AL6
DownloadVisualize
BU of 4al6 by Molmil
Crystal structure of the S148ACsy4-crRNA complex
分子名称: CRRNA, 5'-R(CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP* CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4CMQ
DownloadVisualize
BU of 4cmq by Molmil
Crystal structure of Mn-bound S.pyogenes Cas9
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
著者Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
登録日2014-01-17
公開日2014-02-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
4C97
DownloadVisualize
BU of 4c97 by Molmil
Cas6 (TTHA0078) H37A mutant
分子名称: CAS6A, SULFATE ION
著者Jinek, M, Niewoehner, O, Doudna, J.A.
登録日2013-10-02
公開日2013-11-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
8DC2
DownloadVisualize
BU of 8dc2 by Molmil
Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA
分子名称: CasLambda, DNA NTS, DNA TS, ...
著者Al-Shayeb, B, Skopintsev, P, Soczek, K, Doudna, J.
登録日2022-06-15
公開日2022-12-14
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Cell, 185, 2022
6O1O
DownloadVisualize
BU of 6o1o by Molmil
Cryo-EM structure of the T. thermophilus Csm complex bound to target ssRNA
分子名称: Csm1, Csm2, Csm3, ...
著者Liu, J.J, Liu, T.Y.
登録日2019-02-21
公開日2019-07-10
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble.
Nat Commun, 10, 2019
7WB0
DownloadVisualize
BU of 7wb0 by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state with flexible H2 domain
分子名称: NTS-DNA, RNA (115-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAZ
DownloadVisualize
BU of 7waz by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at ts loading state
分子名称: NTS-DNA, RNA (115-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAY
DownloadVisualize
BU of 7way by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state
分子名称: DNA (27-MER), DNA (33-MER), RNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB1
DownloadVisualize
BU of 7wb1 by Molmil
PlmCasX-sgRNAv2-dsDNA ternary complex at nts loading state
分子名称: NTS-DNA, RNA (121-MER), TS-DNA, ...
著者Zhang, S, Liu, J.J.G.
登録日2021-12-15
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7LYS
DownloadVisualize
BU of 7lys by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and DNA
分子名称: CasPhi-2, NTS-DNA, TS-DNA, ...
著者Pausch, P, Soczek, K, Nogales, E, Doudna, J.
登録日2021-03-08
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
7LYT
DownloadVisualize
BU of 7lyt by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and Phosphorothioate-DNA
分子名称: CasPhi, MAGNESIUM ION, NTS-DNA*, ...
著者Pausch, P, Soczek, K, Nogales, E, Doudna, J.
登録日2021-03-08
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
7M5O
DownloadVisualize
BU of 7m5o by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA
分子名称: CasPhi, ZINC ION, crRNA
著者Pausch, P, Soczek, K, Nogales, E, Doudna, J.
登録日2021-03-24
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
8FYA
DownloadVisualize
BU of 8fya by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:PAM-containing prespacer complex
分子名称: Cas1, Cas2-DEDDh, DNA (28-MER), ...
著者Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
登録日2023-01-25
公開日2023-05-03
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FYB
DownloadVisualize
BU of 8fyb by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex
分子名称: Cas1, Cas2-DEDDh, DNA (17-MER), ...
著者Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
登録日2023-01-25
公開日2023-05-03
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FYC
DownloadVisualize
BU of 8fyc by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex linear CRISPR repeat conformation
分子名称: Cas1, Cas2-DEDDh, DEDDh, ...
著者Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
登録日2023-01-25
公開日2023-05-03
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FY9
DownloadVisualize
BU of 8fy9 by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:PAM-deficient prespacer complex
分子名称: Cas1, Cas2-DEDDh, DNA (28-MER)
著者Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
登録日2023-01-25
公開日2023-05-03
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FYD
DownloadVisualize
BU of 8fyd by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex bent CRISPR repeat conformation
分子名称: Cas1, Cas2-DEDDh, DNA (13-MER), ...
著者Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
登録日2023-01-25
公開日2023-05-03
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
1HR2
DownloadVisualize
BU of 1hr2 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.
分子名称: MAGNESIUM ION, P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN
著者Juneau, K, Podell, E.R, Harrington, D.J, Cech, T.R.
登録日2000-12-20
公開日2001-04-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9, 2001
3GOD
DownloadVisualize
BU of 3god by Molmil
Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated antiviral defense
分子名称: CALCIUM ION, Cas1, MANGANESE (II) ION, ...
著者Wiedenheft, B.
登録日2009-03-18
公開日2009-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for DNase Activity of a Conserved Protein Implicated in CRISPR-Mediated Genome Defense.
Structure, 17, 2009
280D
DownloadVisualize
BU of 280d by Molmil
THE STRUCTURE OF AN RNA DODECAMER SHOWS HOW TANDEM U-U BASE PAIRS INCREASE THE RANGE OF STABLE RNA STRUCTURES AND THE DIVERSITY OF RECOGNITION SITES
分子名称: RNA (5'-R(*GP*GP*CP*GP*CP*UP*UP*GP*CP*GP*UP*C)-3')
著者Lietzke, S.E, Barnes, C.L, Kundrot, C.E.
登録日1996-08-22
公開日1996-09-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites.
Structure, 4, 1996
3LQX
DownloadVisualize
BU of 3lqx by Molmil
SRP ribonucleoprotein core complexed with cobalt hexammine
分子名称: CHLORIDE ION, COBALT HEXAMMINE(III), POTASSIUM ION, ...
著者Batey, R.T.
登録日2010-02-10
公開日2010-03-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural and Energetic Analysis of Metal Ions Essential to SRP Signal Recognition Domain Assembly
Biochemistry, 41, 2002
5L1Z
DownloadVisualize
BU of 5l1z by Molmil
TAR complex with HIV-1 Tat-AFF4-P-TEFb
分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ...
著者Schulze-Gahmen, U, Hurley, J.
登録日2016-07-29
公開日2016-10-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Elife, 5, 2016

219515

件を2024-05-08に公開中

PDB statisticsPDBj update infoContact PDBjnumon