8DC2

Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA

Summary for 8DC2

Entry DOI	10.2210/pdb8dc2/pdb
EMDB information	27320
Descriptor	CasLambda, RNA (51-MER), DNA TS, ... (4 entities in total)
Functional Keywords	crispr, rna binding protein, dna binding protein, phage, viral protein, enzyme, ribonucleoprotein, rna binding protein-rna-dna complex, rna binding protein/rna/dna
Biological source	uncultured virus More
Total number of polymer chains	4
Total formula weight	132489.14
Authors	Al-Shayeb, B.,Skopintsev, P.,Soczek, K.,Doudna, J. (deposition date: 2022-06-15, release date: 2022-12-14)
Primary citation	Al-Shayeb, B.,Skopintsev, P.,Soczek, K.M.,Stahl, E.C.,Li, Z.,Groover, E.,Smock, D.,Eggers, A.R.,Pausch, P.,Cress, B.F.,Huang, C.J.,Staskawicz, B.,Savage, D.F.,Jacobsen, S.E.,Banfield, J.F.,Doudna, J.A. Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors. Cell, 185:4574-4586.e16, 2022 Cited by PubMed: 36423580 DOI: 10.1016/j.cell.2022.10.020 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.99 Å)

Structure validation