280D

THE STRUCTURE OF AN RNA DODECAMER SHOWS HOW TANDEM U-U BASE PAIRS INCREASE THE RANGE OF STABLE RNA STRUCTURES AND THE DIVERSITY OF RECOGNITION SITES

Summary for 280D

• Entry DOI: 10.2210/pdb280d/pdb
• Descriptor: RNA (5'-R(*GP*GP*CP*GP*CP*UP*UP*GP*CP*GP*UP*C)-3') (2 entities in total)
• Functional Keywords: unusual rna, double helix, internal loop, mismatched, rna
• Total number of polymer chains: 4
• Total formula weight: 15281.18

Authors

Lietzke, S.E.,Barnes, C.L.,Kundrot, C.E. (deposition date: 1996-08-22, release date: 1996-09-30, Last modification date: 2024-04-03)

Primary citation

Lietzke, S.E.,Barnes, C.L.,Berglund, J.A.,Kundrot, C.E.
The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites.
Structure, 4:917-930, 1996

PubMed Abstract: Non-canonical base pairs are fundamental building blocks of RNA structures. They can adopt geometries quite different from those of canonical base pairs and are common in RNA molecules that do not transfer sequence information. Tandem U-U base pairs occur frequently, and can stabilize duplex formation despite the fact that a single U-U base pair is destabilizing.

PubMed: 8805576
DOI: 10.1016/S0969-2126(96)00099-8

Experimental method

X-RAY DIFFRACTION (2.4 Å)