1B3R
 
 | | RAT LIVER S-ADENOSYLHOMOCYSTEIN HYDROLASE | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (S-ADENOSYLHOMOCYSTEINE HYDROLASE) | | Authors: | Hu, Y, Komoto, J, Huang, Y, Takusagawa, F, Gomi, T, Ogawa, H, Takata, Y, Fujioka, M. | | Deposit date: | 1998-12-14 | | Release date: | 1998-12-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.
Biochemistry, 38, 1999
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5ZR0
 | | Solution structure of peptidyl-prolyl cis/trans isomerase domain of Trigger Factor in complex with MBP | | Descriptor: | Maltose-binding periplasmic protein,Trigger factor | | Authors: | Kawagoe, S, Nakagawa, H, Kumeta, H, Ishimori, K, Saio, T. | | Deposit date: | 2018-04-21 | | Release date: | 2018-08-22 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural insight into prolinecis/transisomerization of unfolded proteins catalyzed by the trigger factor chaperone.
J. Biol. Chem., 293, 2018
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1D8L
 | | E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III | | Descriptor: | PROTEIN (HOLLIDAY JUNCTION DNA HELICASE RUVA) | | Authors: | Nishino, T, Iwasaki, H, Kataoka, M, Ariyoshi, M, Fujita, T, Shinagawa, H, Morikawa, K. | | Deposit date: | 1999-10-25 | | Release date: | 2000-05-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Modulation of RuvB function by the mobile domain III of the Holliday junction recognition protein RuvA.
J.Mol.Biol., 298, 2000
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2LI5
 | | NMR structure of Atg8-Atg7C30 complex | | Descriptor: | Autophagy-related protein 8, Ubiquitin-like modifier-activating enzyme ATG7 | | Authors: | Kumeta, H, Satoo, K, Noda, N.N, Fujioka, Y, Ogura, K, Nakatogawa, H, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2011-08-23 | | Release date: | 2011-11-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol.Cell, 44, 2011
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1C7Y
 | | E.COLI RUVA-HOLLIDAY JUNCTION COMPLEX | | Descriptor: | DNA (5'-D(P*DAP*DAP*DGP*DTP*DTP*DGP*DGP*DGP*DAP*DTP*DTP*DGP*DT)-3'), DNA (5'-D(P*DCP*DAP*DAP*DTP*DCP*DCP*DCP*DAP*DAP*DCP*DTP*DT)-3'), DNA (5'-D(P*DCP*DGP*DAP*DAP*DTP*DGP*DTP*DGP*DTP*DGP*DTP*DCP*DT)-3'), ... | | Authors: | Ariyoshi, M, Nishino, T, Iwasaki, H, Shinagawa, H, Morikawa, K. | | Deposit date: | 2000-04-03 | | Release date: | 2000-07-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of the holliday junction DNA in complex with a single RuvA tetramer.
Proc.Natl.Acad.Sci.USA, 97, 2000
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7BT2
 | | Crystal structure of the SERCA2a in the E2.ATP state | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Kabashima, Y, Ogawa, H, Nakajima, R, Toyoshima, C. | | Deposit date: | 2020-03-31 | | Release date: | 2020-07-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.00002861 Å) | | Cite: | What ATP binding does to the Ca2+pump and how nonproductive phosphoryl transfer is prevented in the absence of Ca2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7VML
 | | Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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2K6Q
 | | LC3 p62 complex structure | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | | Authors: | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2008-07-17 | | Release date: | 2008-09-02 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
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2KWC
 | | The NMR structure of the autophagy-related protein Atg8 | | Descriptor: | Autophagy-related protein 8 | | Authors: | Kumeta, H, Watanabe, M, Nakatogawa, H, Yamaguchi, M, Ogura, K, Adachi, W, Fujioka, Y, Noda, N.N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-05-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of the autophagy-related protein Atg8
J.Biomol.Nmr, 47, 2010
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2RUH
 | | Chemical Shift Assignments for MIP and MDM2 in bound state | | Descriptor: | E3 ubiquitin-protein ligase Mdm2 | | Authors: | Nagata, T, Shirakawa, K, Kobayashi, N, Shiheido, H, Horisawa, K, Katahira, M, Doi, N, Yanagawa, H. | | Deposit date: | 2014-06-03 | | Release date: | 2014-10-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Inhibition of the MDM2:p53 Interaction by an Optimized MDM2-Binding Peptide Selected with mRNA Display
Plos One, 9, 2014
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4YCN
 | | Crystal structure of the calcium pump with bound marine macrolide BLLB | | Descriptor: | (4S,5E,8S,9E,11S,13E,15E,18R)-4-hydroxy-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]oxacyclooctadeca-5,9,13,15-tetraen-2-one, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | | Authors: | Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C. | | Deposit date: | 2015-02-20 | | Release date: | 2016-01-13 | | Last modified: | 2020-02-05 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
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4YCM
 | | Crystal structure of the calcium pump with bound marine macrolide BLS | | Descriptor: | (4S,5E,8S,9E,11S,13E,15E,18R)-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]-2-oxooxacyclooctadeca-5,9,13,15-tetraen-4-yl 3-O-methyl-beta-D-glucopyranoside, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | | Authors: | Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C. | | Deposit date: | 2015-02-20 | | Release date: | 2016-01-13 | | Last modified: | 2020-02-05 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
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3A5T
 | | Crystal structure of MafG-DNA complex | | Descriptor: | 5'-D(*CP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*G)-3', MAGNESIUM ION, ... | | Authors: | Kurokawa, H, Motohashi, H, Sueno, S, Kimura, M, Takagawa, H, Kanno, Y, Yamamoto, M, Tanaka, T. | | Deposit date: | 2009-08-11 | | Release date: | 2009-10-13 | | Last modified: | 2023-06-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Basis of Alternative DNA Recognition by Maf Transcription Factors
Mol.Cell.Biol., 29, 2009
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1K0U
 | | Inhibition of S-adenosylhomocysteine Hydrolase by "acyclic sugar" Adenosine Analogue D-eritadenine | | Descriptor: | D-ERITADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE | | Authors: | Takusagawa, F, Huang, Y, Komoto, J, Takata, Y, Gomi, T, Ogawa, H, Fujioka, M, Powell, D. | | Deposit date: | 2001-09-20 | | Release date: | 2001-10-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.
J.Biol.Chem., 277, 2002
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1IPC
 | | CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GTP | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | | Authors: | Tomoo, K, Shen, X, Okabe, K, Nozoe, Y, Fukuhara, S, Morino, S, Ishida, T, Taniguchi, T, Hasegawa, H, Terashima, A, Sasaki, M, Katsuya, Y, Kitamura, K, Miyoshi, H, Ishikawa, M, Miura, K. | | Deposit date: | 2001-05-08 | | Release date: | 2002-05-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and
P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic
initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002
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1HJP
 | | HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI | | Descriptor: | RUVA | | Authors: | Nishino, T, Ariyoshi, M, Iwasaki, H, Shinagawa, H, Morikawa, K. | | Deposit date: | 1997-08-21 | | Release date: | 1998-02-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Functional Analyses of the Domain Structure in the Holliday Junction Binding Protein Ruva
Structure, 6, 1998
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5ZCN
 | | Solution NMR structure of a new lasso peptide brevunsin | | Descriptor: | brevunsin | | Authors: | Hemmi, H, Kodani, S, Miyake, Y, Kaweewan, I, Nakagawa, H. | | Deposit date: | 2018-02-19 | | Release date: | 2018-10-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Heterologous production of a new lasso peptide brevunsin in Sphingomonas subterranea
J. Ind. Microbiol. Biotechnol., 45, 2018
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1IWA
 | | RUBISCO FROM GALDIERIA PARTITA | | Descriptor: | SULFATE ION, ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit | | Authors: | Okano, Y, Mizohata, E, Xie, Y, Matsumura, H, Sugawara, H, Inoue, T, Yokota, A, Kai, Y. | | Deposit date: | 2002-04-30 | | Release date: | 2003-04-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | X-Ray Structure of Galdieria Rubisco Complexed with one sulfate ion per active site
FEBS LETT., 527, 2002
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1IXR
 | | RuvA-RuvB complex | | Descriptor: | Holliday junction DNA helicase ruvA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RuvB | | Authors: | Yamada, K, Miyata, T, Tsuchiya, D, Oyama, T, Fujiwara, Y, Ohnishi, T, Iwasaki, H, Shinagawa, H, Ariyoshi, M, Mayanagi, K, Morikawa, K. | | Deposit date: | 2002-07-04 | | Release date: | 2002-11-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structure of the RuvA-RuvB Complex: A Structural Basis for the Holliday Junction Migrating Motor Machinery
Mol.Cell, 10, 2002
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1IPB
 | | CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GPPPA | | Descriptor: | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | | Authors: | Tomoo, K, Shen, X, Okabe, K, Nozoe, Y, Fukuhara, S, Morino, S, Ishida, T, Taniguchi, T, Hasegawa, H, Terashima, A, Sasaki, M, Katsuya, Y, Kitamura, K, Miyoshi, H, Ishikawa, M, Miura, K. | | Deposit date: | 2001-05-08 | | Release date: | 2002-05-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and
P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic
initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002
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1IXS
 | | Structure of RuvB complexed with RuvA domain III | | Descriptor: | Holliday junction DNA helicase ruvA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RuvB | | Authors: | Yamada, K, Miyata, T, Tsuchiya, D, Oyama, T, Fujiwara, Y, Ohnishi, T, Iwasaki, H, Shinagawa, H, Ariyoshi, M, Mayanagi, K, Morikawa, K. | | Deposit date: | 2002-07-04 | | Release date: | 2002-11-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal Structure of the RuvA-RuvB Complex: A Structural Basis for the Holliday Junction Migrating Motor Machinery
Mol.Cell, 10, 2002
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3VW6
 | | Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor | | Descriptor: | 4-tert-butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide, Mitogen-activated protein kinase kinase kinase 5 | | Authors: | Terao, Y, Suzuki, H, Yoshikawa, M, Yashiro, H, Takekawa, S, Fujitani, Y, Okada, K, Inoue, Y, Yamamoto, Y, Nakagawa, H, Yao, S, Kawamoto, T, Uchikawa, O. | | Deposit date: | 2012-08-06 | | Release date: | 2012-10-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors.
Bioorg. Med. Chem. Lett., 22, 2012
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1ON8
 | | Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) with UDP and GlcUAb(1-3)Galb(1-O)-naphthalenelmethanol an acceptor substrate analog | | Descriptor: | 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ... | | Authors: | Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M. | | Deposit date: | 2003-02-27 | | Release date: | 2003-04-22 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
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3W5A
 | | Crystal structure of the calcium pump and sarcolipin from rabbit fast twitch skeletal muscle in the E1.Mg2+ state | | Descriptor: | 2',3'-O-[(1r)-2,4,6-trinitrocyclohexa-2,5-diene-1,1-diyl]adenosine 5'-(dihydrogen phosphate), MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Toyoshima, C, Iwasawa, S, Ogawa, H, Hirata, A, Tsueda, J, Inesi, G. | | Deposit date: | 2013-01-27 | | Release date: | 2013-03-06 | | Last modified: | 2013-03-27 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state.
Nature, 495, 2013
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3W5D
 | | Crystal structure of the calcium pump in the E2+Pi state | | Descriptor: | PHOSPHATIDYLETHANOLAMINE, SERCA1a, SODIUM ION, ... | | Authors: | Toyoshima, C, Iwasawa, S, Ogawa, H, Hirata, A, Tsueda, J, Inesi, G. | | Deposit date: | 2013-01-27 | | Release date: | 2013-03-06 | | Last modified: | 2013-03-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state.
Nature, 495, 2013
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