5JH9
 
 | | Crystal structure of prApe1 | | Descriptor: | CACODYLATE ION, Vacuolar aminopeptidase 1, ZINC ION | | Authors: | Noda, N.N, Adachi, W, Inagaki, F. | | Deposit date: | 2016-04-20 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates
Cell Rep, 16, 2016
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5JGF
 | | Crystal structure of mApe1 | | Descriptor: | Vacuolar aminopeptidase 1, ZINC ION | | Authors: | Noda, N.N, Adachi, W, Inagaki, F. | | Deposit date: | 2016-04-20 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates
Cell Rep, 16, 2016
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7VEC
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7W3N
 | | Crystal structure of Ufm1 fused to UFBP1 UFIM | | Descriptor: | UFBP1 peptide,Ubiquitin-fold modifier 1 | | Authors: | Noda, N.N. | | Deposit date: | 2021-11-25 | | Release date: | 2022-12-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Nat Commun, 13, 2022
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7W3O
 | | Crystal structure of human CYB5R3 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 soluble form | | Authors: | Noda, N.N. | | Deposit date: | 2021-11-25 | | Release date: | 2022-12-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Nat Commun, 13, 2022
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2K6Q
 | | LC3 p62 complex structure | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | | Authors: | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2008-07-17 | | Release date: | 2008-09-02 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
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2ZPN
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3VXW
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3VH3
 | | Crystal structure of Atg7CTD-Atg8 complex | | Descriptor: | Autophagy-related protein 8, Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION | | Authors: | Noda, N.N, Satoo, K, Inagaki, F. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol.Cell, 44, 2011
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3VH4
 | | Crystal structure of Atg7CTD-Atg8-MgATP complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Autophagy-related protein 8, MAGNESIUM ION, ... | | Authors: | Noda, N.N, Satoo, K, Inagaki, F. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol.Cell, 44, 2011
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3VP7
 | | Crystal structure of the beta-alpha repeated, autophagy-specific (BARA) domain of Vps30/Atg6 | | Descriptor: | Vacuolar protein sorting-associated protein 30 | | Authors: | Noda, N.N, Kobayashi, T, Adachi, W, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2012-02-28 | | Release date: | 2012-03-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy.
J.Biol.Chem., 287, 2012
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3W1S
 | | Crystal structure of Saccharomyces cerevisiae Atg12-Atg5 conjugate bound to the N-terminal domain of Atg16 | | Descriptor: | Autophagy protein 16, Autophagy protein 5, Ubiquitin-like protein ATG12 | | Authors: | Noda, N.N, Fujioka, Y, Hanada, T, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2012-11-20 | | Release date: | 2012-12-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation
Embo Rep., 14, 2013
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3VH2
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3VH1
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4DVY
 | | Crystal structure of the Helicobacter pylori CagA oncoprotein | | Descriptor: | Cytotoxicity-associated immunodominant antigen | | Authors: | Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M. | | Deposit date: | 2012-02-23 | | Release date: | 2012-07-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA
Cell Host Microbe, 12, 2012
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4DVZ
 | | Crystal structure of the Helicobacter pylori CagA oncoprotein | | Descriptor: | Cytotoxicity-associated immunodominant antigen | | Authors: | Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M. | | Deposit date: | 2012-02-23 | | Release date: | 2012-07-25 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA
Cell Host Microbe, 12, 2012
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4YK8
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7W36
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2KZB
 | | Solution structure of alpha-mannosidase binding domain of Atg19 | | Descriptor: | Autophagy-related protein 19 | | Authors: | Watanabe, Y, Noda, N, Kumeta, H, Suzuki, K, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2010-06-15 | | Release date: | 2010-07-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34.
J.Biol.Chem., 285, 2010
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2KZK
 | | Solution structure of alpha-mannosidase binding domain of Atg34 | | Descriptor: | Uncharacterized protein YOL083W | | Authors: | Watanabe, Y, Noda, N, Kumeta, H, Suzuki, K, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2010-06-18 | | Release date: | 2010-07-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34.
J.Biol.Chem., 285, 2010
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7EU4
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7F2X
 | | Crystal structure of MEK1 C121S mutant | | Descriptor: | MEK1 F11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Fujioka, Y, Noda, N.N. | | Deposit date: | 2021-06-15 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.007 Å) | | Cite: | Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun, 13, 2022
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5H9V
 | | Crystal structure of Regnase PIN domain, form I | | Descriptor: | Ribonuclease ZC3H12A, SODIUM ION | | Authors: | Yokogawa, M, Tsushima, T, Adachi, W, Noda, N.N, Inagaki, F. | | Deposit date: | 2015-12-29 | | Release date: | 2016-03-16 | | Last modified: | 2020-02-19 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions
Sci Rep, 6, 2016
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5H9W
 | | Crystal structure of Regnase PIN domain, form II | | Descriptor: | Ribonuclease ZC3H12A, SODIUM ION | | Authors: | Yokogawa, M, Tsushima, T, Adachi, W, Noda, N.N, Inagaki, F. | | Deposit date: | 2015-12-29 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions
Sci Rep, 6, 2016
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5JHF
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