7VML

Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state)

This is a non-PDB format compatible entry.

Summary for 7VML

• Entry DOI: 10.2210/pdb7vml/pdb
• EMDB information: 33935
• Descriptor: Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION (3 entities in total)
• Functional Keywords: calcium, calcium channel, calcium transport, ion transport, ionic channel, metal transport, er/sr membrane, ryanodine receptor, ryanodine, receptor, wild type, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 2210813.15

Authors

Kobayashi, T.,Tsutsumi, A.,Kurebayashi, N.,Kodama, M.,Kikkawa, M.,Murayama, T.,Ogawa, H. (deposition date: 2021-10-09, release date: 2022-08-10, Last modification date: 2024-06-19)

• Primary citation: Kobayashi, T.,Tsutsumi, A.,Kurebayashi, N.,Saito, K.,Kodama, M.,Sakurai, T.,Kikkawa, M.,Murayama, T.,Ogawa, H.; Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.; Nat Commun, 13:2821-2821, 2022; PubMed: 35595836; DOI: 10.1038/s41467-022-30429-x

Experimental method

ELECTRON MICROSCOPY (3.3 Å)