1ON8
Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) with UDP and GlcUAb(1-3)Galb(1-O)-naphthalenelmethanol an acceptor substrate analog
Summary for 1ON8
Entry DOI | 10.2210/pdb1on8/pdb |
Related | 1OMX 1OMZ 1ON6 |
Descriptor | Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, beta-D-glucopyranuronic acid-(1-3)-beta-D-galactopyranose, MANGANESE (II) ION, ... (6 entities in total) |
Functional Keywords | rossmann fold, dxd motif, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Endoplasmic reticulum membrane ; Single-pass type II membrane protein : Q9ES89 |
Total number of polymer chains | 2 |
Total formula weight | 68547.52 |
Authors | Pedersen, L.C.,Dong, J.,Taniguchi, F.,Kitagawa, H.,Krahn, J.M.,Pedersen, L.G.,Sugahara, K.,Negishi, M. (deposition date: 2003-02-27, release date: 2003-04-22, Last modification date: 2023-08-16) |
Primary citation | Pedersen, L.C.,Dong, J.,Taniguchi, F.,Kitagawa, H.,Krahn, J.M.,Pedersen, L.G.,Sugahara, K.,Negishi, M. Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis J.Biol.Chem., 278:14420-14428, 2003 Cited by PubMed: 12562774DOI: 10.1074/jbc.M210532200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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