1IPB

CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GPPPA

Summary for 1IPB

• Entry DOI: 10.2210/pdb1ipb/pdb
• Related: 1IPC
• Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: initiation factor, protein biosynthesis, rna binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, P-body : P06730
• Total number of polymer chains: 1
• Total formula weight: 25917.68

Authors

Tomoo, K.,Shen, X.,Okabe, K.,Nozoe, Y.,Fukuhara, S.,Morino, S.,Ishida, T.,Taniguchi, T.,Hasegawa, H.,Terashima, A.,Sasaki, M.,Katsuya, Y.,Kitamura, K.,Miyoshi, H.,Ishikawa, M.,Miura, K. (deposition date: 2001-05-08, release date: 2002-05-08, Last modification date: 2023-12-27)

• Primary citation: Tomoo, K.,Shen, X.,Okabe, K.,Nozoe, Y.,Fukuhara, S.,Morino, S.,Ishida, T.,Taniguchi, T.,Hasegawa, H.,Terashima, A.,Sasaki, M.,Katsuya, Y.,Kitamura, K.,Miyoshi, H.,Ishikawa, M.,Miura, K.; Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region; BIOCHEM.J., 362:539-544, 2002; PubMed: 11879179; DOI: 10.1042/0264-6021:3620539

Experimental method

X-RAY DIFFRACTION (2 Å)