8JDV
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![BU of 8jdv by Molmil](/molmil-images/mine/8jdv) | Crystal structure of mLDHD in complex with 2-ketohexanoic acid | Descriptor: | 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDG
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![BU of 8jdg by Molmil](/molmil-images/mine/8jdg) | Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid | Descriptor: | (2R)-2-oxidanylbutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-14 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDR
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![BU of 8jdr by Molmil](/molmil-images/mine/8jdr) | Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid | Descriptor: | (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDD
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![BU of 8jdd by Molmil](/molmil-images/mine/8jdd) | Crystal structure of H405A mLDHD in apo form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDZ
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![BU of 8jdz by Molmil](/molmil-images/mine/8jdz) | Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid | Descriptor: | (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDU
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![BU of 8jdu by Molmil](/molmil-images/mine/8jdu) | Crystal structure of mLDHD in complex with 2-ketovaleric acid | Descriptor: | 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDY
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![BU of 8jdy by Molmil](/molmil-images/mine/8jdy) | Crystal structure of mLDHD in complex with 2-ketoisocaproic acid | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDF
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![BU of 8jdf by Molmil](/molmil-images/mine/8jdf) | Crystal structure of H405A mLDHD in complex with D-lactate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDX
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![BU of 8jdx by Molmil](/molmil-images/mine/8jdx) | Crystal structure of mLDHD in complex with 2-ketoisovaleric acid | Descriptor: | 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDE
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![BU of 8jde by Molmil](/molmil-images/mine/8jde) | Crystal structure of mLDHD in complex with D-lactate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.729 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDO
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![BU of 8jdo by Molmil](/molmil-images/mine/8jdo) | Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid | Descriptor: | (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDP
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![BU of 8jdp by Molmil](/molmil-images/mine/8jdp) | Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid | Descriptor: | DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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5ZHY
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![BU of 5zhy by Molmil](/molmil-images/mine/5zhy) | Structural characterization of the HCoV-229E fusion core | Descriptor: | Spike glycoprotein | Authors: | Zhang, W, Zheng, Q, Yan, M, Chen, X, Yang, H, Zhou, W, Rao, Z. | Deposit date: | 2018-03-13 | Release date: | 2018-06-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.441 Å) | Cite: | Structural characterization of the HCoV-229E fusion core. Biochem. Biophys. Res. Commun., 497, 2018
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8HHG
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![BU of 8hhg by Molmil](/molmil-images/mine/8hhg) | The bacterial divisome protein complex FtsB-FtsL-FtsQ | Descriptor: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-11-16 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun, 14, 2023
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8HHH
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![BU of 8hhh by Molmil](/molmil-images/mine/8hhh) | The bacterial divisome protein complex FtsB-FtsL-FtsQ | Descriptor: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-11-16 | Release date: | 2023-04-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun, 14, 2023
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8HHF
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![BU of 8hhf by Molmil](/molmil-images/mine/8hhf) | The bacterial divisome protein complex FtsB-FtsL-FtsQ | Descriptor: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-11-16 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun, 14, 2023
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7CN9
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![BU of 7cn9 by Molmil](/molmil-images/mine/7cn9) | Cryo-EM structure of SARS-CoV-2 Spike ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ho, M, Chang, Y, Wang, C, Wu, Y, Huang, H, Chen, T, Lo, J.M, Chen, X, Ma, C. | Deposit date: | 2020-07-30 | Release date: | 2020-08-26 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2. Cell Rep, 32, 2020
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7WF5
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![BU of 7wf5 by Molmil](/molmil-images/mine/7wf5) | c-Src in complex with ponatinib | Descriptor: | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase Src | Authors: | Guo, M, Duan, Y, Dai, S, Chen, X, Chen, Y. | Deposit date: | 2021-12-26 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Structural study of ponatinib in inhibiting SRC kinase. Biochem.Biophys.Res.Commun., 598, 2022
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6L03
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![BU of 6l03 by Molmil](/molmil-images/mine/6l03) | structure of PTP-MEG2 and MUNC18-1-pY145 peptide complex | Descriptor: | Tyrosine-protein phosphatase non-receptor type 9, stxbp1-pY145 peptide | Authors: | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | Deposit date: | 2019-09-25 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.084 Å) | Cite: | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
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6KZQ
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![BU of 6kzq by Molmil](/molmil-images/mine/6kzq) | structure of PTP-MEG2 and NSF-pY83 peptide complex | Descriptor: | NSF-pY83 peptide, Tyrosine-protein phosphatase non-receptor type 9 | Authors: | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | Deposit date: | 2019-09-25 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
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3K71
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![BU of 3k71 by Molmil](/molmil-images/mine/3k71) | Structure of integrin alphaX beta2 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | Deposit date: | 2009-10-11 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4. Embo J., 29, 2010
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3K5K
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![BU of 3k5k by Molmil](/molmil-images/mine/3k5k) | Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a | Descriptor: | 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, CHLORIDE ION, Histone-lysine N-methyltransferase, ... | Authors: | Dong, A, Wasney, G.A, Liu, F, Chen, X, Allali-Hassani, A, Senisterra, G, Chau, I, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Frye, S.V, Bochkarev, A, Brown, P.J, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-07 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J.Med.Chem., 52, 2009
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3K72
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![BU of 3k72 by Molmil](/molmil-images/mine/3k72) | Structure of integrin alphaX beta2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | Deposit date: | 2009-10-11 | Release date: | 2010-01-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4. Embo J., 29, 2010
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3K6S
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![BU of 3k6s by Molmil](/molmil-images/mine/3k6s) | Structure of integrin alphaXbeta2 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | Deposit date: | 2009-10-09 | Release date: | 2010-01-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of an integrin with an alphaI domain, complement receptor type 4. Embo J., 29, 2010
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7WLT
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![BU of 7wlt by Molmil](/molmil-images/mine/7wlt) | the Curved Structure of mPIEZO1 in Lipid Bilayer | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... | Authors: | Yang, X, Lin, C, Chen, X, Li, S, Li, X, Xiao, B. | Deposit date: | 2022-01-13 | Release date: | 2022-04-13 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure deformation and curvature sensing of PIEZO1 in lipid membranes. Nature, 604, 2022
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