8W78

Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase in complex with FAD and 2-oxoglutarate

Summary for 8W78

Entry DOI	10.2210/pdb8w78/pdb
Descriptor	FI05204p, FLAVIN-ADENINE DINUCLEOTIDE, 2-OXOGLUTARIC ACID, ... (4 entities in total)
Functional Keywords	l-2-hydroxyglutarate dehydrogenase, l2hgdh, dehydrogenase, 2-oxoglutarate, oxidoreductase
Biological source	Drosophila melanogaster (fruit fly)
Total number of polymer chains	4
Total formula weight	189444.35
Authors	Yang, J.,Chen, X.,Jin, S.,Ding, J. (deposition date: 2023-08-30, release date: 2023-11-29, Last modification date: 2023-12-20)
Primary citation	Yang, J.,Chen, X.,Jin, S.,Ding, J. Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria. J.Biol.Chem., 300:105491-105491, 2023 Cited by PubMed: 37995940 DOI: 10.1016/j.jbc.2023.105491 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation