8IS2

Crystal structure of a polyketide aromatase/cyclase Abx(+)D from Actinomycetes sp. MA7150.

Summary for 8IS2

• Entry DOI: 10.2210/pdb8is2/pdb
• Descriptor: Cyclase (2 entities in total)
• Functional Keywords: aromatase, cyclase, polyketide, biosynthetic protein
• Biological source: uncultured actinomycete
• Total number of polymer chains: 2
• Total formula weight: 26880.20

Authors

Luo, S.,Chen, X. (deposition date: 2023-03-20, release date: 2024-02-28, Last modification date: 2024-03-20)

• Primary citation: Jiang, K.,Chen, X.,Yan, X.,Li, G.,Lin, Z.,Deng, Z.,Luo, S.,Qu, X.; An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin.; Proc.Natl.Acad.Sci.USA, 121:e2321722121-e2321722121, 2024; PubMed: 38446858; DOI: 10.1073/pnas.2321722121

Experimental method

X-RAY DIFFRACTION (1.32 Å)