Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5WAH
DownloadVisualize
BU of 5wah by Molmil
SOLUTION NMR STRUCTURE OF SIGLEC-5 BINDING DOMAIN FROM STREPTOCOCCAL BETA PROTEIN
分子名称: IgA FC receptor
著者ELETSKY, A, CHEN, C, FONG, J.J, NIZET, V, VARKI, A, PRESTEGARD, J.H.
登録日2017-06-26
公開日2018-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献SOLUTION NMR STRUCTURE OF SIGLEC-5 BINDING DOMAIN FROM STREPTOCOCCAL BETA PROTEIN
To Be Published
2XNY
DownloadVisualize
BU of 2xny by Molmil
A fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (7.5 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
2XNX
DownloadVisualize
BU of 2xnx by Molmil
BC1 fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
7SAF
DownloadVisualize
BU of 7saf by Molmil
Fragment of streptococcal M87 protein fused to GCN4 adaptor
分子名称: General control transcription factor GCN4/M protein chimera, PHOSPHATE ION
著者Kolesinski, P, Ghosh, P.
登録日2021-09-22
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37
Elife, 11, 2022
7SAY
DownloadVisualize
BU of 7say by Molmil
Fragment of streptococcal M87 protein fused to GCN4 adaptor in complex with human cathelicidin
分子名称: 1,2-ETHANEDIOL, Antibacterial peptide LL-37, General control transcription factor GCN4/M protein chimera
著者Kolesinski, P, Ghosh, P.
登録日2021-09-23
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37
Elife, 11, 2022
1S6W
DownloadVisualize
BU of 1s6w by Molmil
Solution Structure of hybrid white striped bass hepcidin
分子名称: Hepcidin
著者Babon, J.J, Singh, S, Pennington, M.W, Norton, R.S, Westerman, M.E.
登録日2004-01-28
公開日2004-12-14
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.
J.Biol.Chem., 280, 2005
3SGT
DownloadVisualize
BU of 3sgt by Molmil
Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1299
分子名称: 2-{[4-(3,4-dimethylphenoxy)phenyl]carbamoyl}benzoic acid, Undecaprenyl pyrophosphate synthase
著者Cao, R, Liu, Y.-L, Oldfield, E.
登録日2011-06-15
公開日2012-12-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
2OTO
DownloadVisualize
BU of 2oto by Molmil
N-terminal fragment of Streptococcus pyogenes M1 protein
分子名称: M protein
著者McNamara, C.W, Ghosh, P.
登録日2007-02-08
公開日2008-03-18
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence.
Science, 319, 2008
8C5N
DownloadVisualize
BU of 8c5n by Molmil
Sub-atomic resolution structure of the chitin-binding protein D (CbpD) from Pseudomonas aeruginosa
分子名称: CHLORIDE ION, Chitin-binding protein CbpD
著者Cordara, G, Krengel, U, Golten, O, Vaaje-Kolstad, G, Vinther Soerensen, H.
登録日2023-01-09
公開日2023-06-28
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (0.75 Å)
主引用文献Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia.
Proc.Natl.Acad.Sci.USA, 120, 2023
6UKD
DownloadVisualize
BU of 6ukd by Molmil
Co-complex of S. pyogenes 10782 streptopain bound with a nitrile-based specific covalent inhibitor
分子名称: NITRATE ION, Streptopain, benzyl [(2S)-1-(3-nitrophenyl)-3-oxobutan-2-yl]carbamate
著者Wolan, D.W, Woehl, J.L, Kitamura, S.
登録日2019-10-04
公開日2020-09-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.589 Å)
主引用文献An Irreversible Inhibitor to Probe the Role ofStreptococcus pyogenesCysteine Protease SpeB in Evasion of Host Complement Defenses.
Acs Chem.Biol., 15, 2020
6UQD
DownloadVisualize
BU of 6uqd by Molmil
Co-complex of S. pyogenes 10782 streptopain bound with a SuFEx-based optimized small molecule inhibitor
分子名称: Streptopain, benzyl [(1S)-2-(3-{[(4-carbamoylpiperidin-1-yl)(fluoro)oxo-lambda~6~-sulfanylidene]amino}phenyl)-1-cyanoethyl]carbamate
著者Wolan, D.W, Woehl, J.L, Kitamura, S.
登録日2019-10-18
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.
J.Am.Chem.Soc., 142, 2020
2ZY1
DownloadVisualize
BU of 2zy1 by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-830
分子名称: Dehydrosqualene synthase, dipotassium (2-oxo-2-{[3-(3-phenoxyphenyl)propyl]amino}ethyl)phosphonate
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2009-01-10
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.
J.Med.Chem., 52, 2009
3VJE
DownloadVisualize
BU of 3vje by Molmil
Crystal structure of the Y248A mutant of C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus in complex with zaragozic acid A
分子名称: Dehydrosqualene synthase, Zaragozic acid A
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3VJD
DownloadVisualize
BU of 3vjd by Molmil
Crystal structure of the Y248A mutant of C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus
分子名称: Dehydrosqualene synthase, L(+)-TARTARIC ACID
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3ADZ
DownloadVisualize
BU of 3adz by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with intermediate PSPP
分子名称: Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-31
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3AE0
DownloadVisualize
BU of 3ae0 by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with geranylgeranyl thiopyrophosphate
分子名称: Dehydrosqualene synthase, MAGNESIUM ION, phosphonooxy-[(10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanyl-phosphinic acid
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-31
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3ACW
DownloadVisualize
BU of 3acw by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-651
分子名称: (3R)-3-biphenyl-4-yl-1-azabicyclo[2.2.2]octan-3-ol, Dehydrosqualene synthase
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-13
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
3ACX
DownloadVisualize
BU of 3acx by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673
分子名称: Dehydrosqualene synthase, N-(1-methylethyl)-3-[(3-prop-2-en-1-ylbiphenyl-4-yl)oxy]propan-1-amine
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-13
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
3ACY
DownloadVisualize
BU of 3acy by Molmil
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-702
分子名称: (1R)-4-[3-(2-benzylphenoxy)phenyl]-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase, MAGNESIUM ION
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E.
登録日2010-01-13
公開日2010-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Mechanism of action and inhibition of dehydrosqualene synthase
Proc.Natl.Acad.Sci.USA, 107, 2010
5HZP
DownloadVisualize
BU of 5hzp by Molmil
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein.
分子名称: C4b-binding protein alpha chain, M protein, serotype 49, ...
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-02
公開日2016-07-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5HYP
DownloadVisualize
BU of 5hyp by Molmil
Structure of human C4b-binding protein alpha cain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M28 protein
分子名称: C4b-binding protein alpha chain, M28 protein
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-01
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.024 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5HYT
DownloadVisualize
BU of 5hyt by Molmil
Structure of human C4b-binidng protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M22 protein
分子名称: C4b-binding protein alpha chain, Precursor to Protein Sir22
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-01
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5HYU
DownloadVisualize
BU of 5hyu by Molmil
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M2 protein
分子名称: C4b-binding protein alpha chain, M protein, serotype 2.1
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-01
公開日2016-07-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.561 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
5I0Q
DownloadVisualize
BU of 5i0q by Molmil
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of mutant group A Streptococcus M2 (K65A, N66A) protein
分子名称: C4b-binding protein alpha chain, M protein, serotype 2.1
著者Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P.
登録日2016-02-04
公開日2016-07-20
最終更新日2016-10-26
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
4D7O
DownloadVisualize
BU of 4d7o by Molmil
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(4-(((3-Fluorophenethyl)amino)methyl)phenyl)-4- methylpyridin-2-amine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[4-({[2-(3-fluorophenyl)ethyl]amino}methyl)phenyl]-4-methylpyridin-2-amine, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2014-11-25
公開日2015-07-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus Aureus
Chem.Biol., 22, 2015

 

12>

223532

件を2024-08-07に公開中

PDB statisticsPDBj update infoContact PDBjnumon