7SAY

Fragment of streptococcal M87 protein fused to GCN4 adaptor in complex with human cathelicidin

Summary for 7SAY

• Entry DOI: 10.2210/pdb7say/pdb
• Descriptor: General control transcription factor GCN4/M protein chimera, Antibacterial peptide LL-37, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: complex, virulence factor, antimicrobial peptide, immune system
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 6
• Total formula weight: 43427.23

Authors

Kolesinski, P.,Ghosh, P. (deposition date: 2021-09-23, release date: 2022-07-13, Last modification date: 2023-10-18)

• Primary citation: Kolesinski, P.,Wang, K.C.,Hirose, Y.,Nizet, V.,Ghosh, P.,Stallings, C.L.,Dotsch, V.; An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37; Elife, 11:-, 2022; PubMed: 35726694; DOI: 10.7554/eLife.77989

Experimental method

X-RAY DIFFRACTION (2.1 Å)