Search by PDB author

Crystal structure of human POFUT2
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ...
著者	Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H.
登録日	2012-03-30
公開日	2012-08-08
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (3.003 Å)
主引用文献	Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J., 31, 2012

4AP6

Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ...
著者	Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H.
登録日	2012-03-30
公開日	2012-08-08
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (3.401 Å)
主引用文献	Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J., 31, 2012

2PHH

THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION
分子名称:	ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
著者	Van Derlaan, J.M, Drenth, J, Hol, W.G.J.
登録日	1989-06-19
公開日	1990-10-15
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation. Biochemistry, 28, 1989

1TBQ

CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
分子名称:	RHODNIIN, THROMBIN
著者	Van De Locht, A, Lamba, D, Bode, W.
登録日	1995-03-02
公開日	1996-10-14
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995

1TBR

CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
分子名称:	RHODNIIN, THROMBIN
著者	Van De Locht, A, Lamba, D, Bode, W.
登録日	1995-03-03
公開日	1996-10-14
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995

1PHH

CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH ITS REACTION PRODUCT 3,4-DIHYDROXYBENZOATE
分子名称:	3,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
著者	Schreuder, H.A, Drenth, J.
登録日	1987-11-04
公開日	1988-04-16
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate. J.Mol.Biol., 199, 1988

1TMT

CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者	Priestle, J.P, Gruetter, M.G.
登録日	1994-05-26
公開日	1994-09-30
最終更新日	2022-12-21
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms. Protein Sci., 2, 1993

1TMU

Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Hirudin variant-2, ...
著者	Priestle, J.P, Gruetter, M.G.
登録日	1994-05-26
公開日	1994-09-30
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms. Protein Sci., 2, 1993

1PPB

THE REFINED 1.9 ANGSTROMS CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN: INTERACTION WITH D-PHE-PRO-ARG CHLOROMETHYLKETONE AND SIGNIFICANCE OF THE TYR-PRO-PRO-TRP INSERTION SEGMENT
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
著者	Bode, W.
登録日	1991-10-24
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (1.92 Å)
主引用文献	The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J., 8, 1989

2HGT

STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), Hirulog
著者	Tulinsky, A, Carperos, V.
登録日	1991-06-03
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structure of the hirugen and hirulog 1 complexes of alpha-thrombin. J.Mol.Biol., 221, 1991

6PXJ

Crystal structure of human thrombin mutant I16T
分子名称:	GLYCEROL, MAGNESIUM ION, Thrombin heavy chain, ...
著者	Stojanovski, B, Chen, Z, Koester, S.K, Pelc, L.A, Di Cera, E.
登録日	2019-07-26
公開日	2019-12-18
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9, 2019

1ETS

REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS
分子名称:	1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, EPSILON-THROMBIN
著者	Bode, W, Brandstetter, H.
登録日	1992-07-06
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992

3HTC

THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2
著者	Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W.
登録日	1993-06-11
公開日	1994-01-31
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249, 1990

6PXQ

Crystal structure of human thrombin mutant D194A
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin heavy chain, Thrombin light chain
著者	Stojanovski, B, Chen, Z, Koester, S.K, Pelc, L.A, Di Cera, E.
登録日	2019-07-26
公開日	2019-12-18
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9, 2019

6V64

Crystal structure of human thrombin bound to ppack with tryptophans replaced by 5-F-tryptophan
分子名称:	D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, Thrombin heavy chain, ...
著者	Ruben, E.A, Chen, Z, Di Cera, E.
登録日	2019-12-04
公開日	2020-05-13
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.29 Å)
主引用文献	19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2. J.Biol.Chem., 295, 2020

1PPC

GEOMETRY OF BINDING OF THE BENZAMIDINE-AND ARGININE-BASED INHIBITORS N-ALPHA-(2-NAPHTHYL-SULPHONYL-GLYCYL)-DL-P-AMIDINOPHENYLALANYL-PIPERIDINE (NAPAP) AND (2R,4R)-4-METHYL-1-[N-ALPHA-(3-METHYL-1,2,3,4-TETRAHYDRO-8-QUINOLINESULPHONYL)-L-ARGINYL]-2-PIPERIDINE CARBOXYLIC ACID (MQPA) TO HUMAN ALPHA-THROMBIN: X-RAY CRYSTALLOGRAPHIC DETERMINATION OF THE NAPAP-TRYPSIN COMPLEX AND MODELING OF NAPAP-THROMBIN AND MQPA-THROMBIN
分子名称:	1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, CALCIUM ION, TRYPSIN
著者	Bode, W, Turk, D.
登録日	1991-10-24
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Geometry of binding of the benzamidine- and arginine-based inhibitors N alpha-(2-naphthyl-sulphonyl-glycyl)-DL-p-amidinophenylalanyl-pipe ridine (NAPAP) and (2R,4R)-4-methyl-1-[N alpha-(3-methyl-1,2,3,4-tetrahydr quinolinesulphonyl)-L-arginyl]-2-piperidine carboxylic acid (MQPA) to human alpha-thrombin.X-ray crystallographic determination of the NAPAP-trypsin complex and modeling of NAPAP-thrombin and MQPA-thrombin. Eur.J.Biochem., 193, 1990

1DWE

Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
分子名称:	ALPHA-THROMBIN heavy chain, ALPHA-THROMBIN light chain, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
著者	Banner, D.W, Hadvary, P.
登録日	1992-08-19
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1DWB

CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), BENZAMIDINE, ...
著者	Banner, D.W, Hadvary, P.
登録日	1992-08-19
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (3.16 Å)
主引用文献	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1DWD

CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
分子名称:	1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者	Banner, D.W, Hadvary, P.
登録日	1992-08-19
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1DWC

CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIA, ...
著者	Banner, D.W, Hadvary, P.
登録日	1992-08-19
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

4HTC

THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者	Tulinsky, A, Rydel, T.J, Bode, W, Huber, R.
登録日	1993-06-25
公開日	1994-01-31
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Refined structure of the hirudin-thrombin complex. J.Mol.Biol., 221, 1991

1TOC

STRUCTURE OF SERINE PROTEINASE
分子名称:	ORNITHODORIN, THROMBIN
著者	Van De Locht, A, Huber, R, Bode, W.
登録日	1996-07-20
公開日	1997-07-23
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	The ornithodorin-thrombin crystal structure, a key to the TAP enigma? EMBO J., 15, 1996

1AI8

HUMAN ALPHA-THROMBIN TERNARY COMPLEX WITH THE EXOSITE INHIBITOR HIRUGEN AND ACTIVE SITE INHIBITOR PHCH2OCO-D-DPA-PRO-BOROMPG
分子名称:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIB, ...
著者	Skordalakes, E, Dodson, G, Elgendy, S, Goodwin, C.A, Green, D, Tyrrel, R, Scully, M.F, Freyssinet, J, Kakkar, V.V, Deadman, J.
登録日	1997-05-01
公開日	1997-10-15
最終更新日	2023-08-02
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci., 1, 1992

1PPH

GEOMETRY OF BINDING OF THE NALPHA-TOSYLATED PIPERIDIDES OF M-AMIDINO-, P-AMIDINO-AND P-GUANIDINO PHENYLALANINE TO THROMBIN AND TRYPSIN: X-RAY CRYSTAL STRUCTURES OF THEIR TRYPSIN COMPLEXES AND MODELING OF THEIR THROMBIN COMPLEXES
分子名称:	3-[(2S)-2-{[(4-methylphenyl)sulfonyl]amino}-3-oxo-3-piperidin-1-ylpropyl]benzenecarboximidamide, CALCIUM ION, SULFATE ION, ...
著者	Bode, W, Turk, D.
登録日	1991-10-24
公開日	1994-01-31
最終更新日	2024-06-05
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes. FEBS Lett., 287, 1991

1ETT

REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS
分子名称:	4-[(2S)-2-{[(4-methylphenyl)sulfonyl]amino}-3-oxo-3-(piperidin-1-yl)propyl]benzene-1-carboximidamide, EPSILON-THROMBIN
著者	Bode, W, Brandstetter, H.
登録日	1992-07-06
公開日	1994-01-31
最終更新日	2018-09-12
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992

12 >

全ヒット件数:	29
表示件数:	25
表示順	関連性が高い順