1PPH

GEOMETRY OF BINDING OF THE NALPHA-TOSYLATED PIPERIDIDES OF M-AMIDINO-, P-AMIDINO-AND P-GUANIDINO PHENYLALANINE TO THROMBIN AND TRYPSIN: X-RAY CRYSTAL STRUCTURES OF THEIR TRYPSIN COMPLEXES AND MODELING OF THEIR THROMBIN COMPLEXES

Summary for 1PPH

• Entry DOI: 10.2210/pdb1pph/pdb
• Related PRD ID: PRD_000374
• Descriptor: TRYPSIN, CALCIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Sus scrofa (pig)
• Cellular location: Secreted, extracellular space: P00760
• Total number of polymer chains: 1
• Total formula weight: 23888.98

Authors

Bode, W.,Turk, D. (deposition date: 1991-10-24, release date: 1994-01-31, Last modification date: 2012-12-12)

• Primary citation: Turk, D.,Sturzebecher, J.,Bode, W.; Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes.; FEBS Lett., 287:133-138, 1991; PubMed: 1879520; DOI: 10.1016/0014-5793(91)80033-Y

Experimental method

X-RAY DIFFRACTION (1.9 Å)