2HGT

STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN

Summary for 2HGT

Related PRD IDPRD_001145 PRD_001148
DescriptorALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), Hirulog, ... (5 entities in total)
Functional Keywordshydrolase(serine protease), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space P00734 P00734
Secreted P28504
Total number of polymer chains4
Total molecular weight36076.06
Authors
Tulinsky, A.,Carperos, V. (deposition date: 1991-06-03, release date: 1994-01-31, Last modification date: 2016-11-09)
Primary citation
Skrzypczak-Jankun, E.,Carperos, V.E.,Ravichandran, K.G.,Tulinsky, A.,Westbrook, M.,Maraganore, J.M.
Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.
J.Mol.Biol., 221:1379-1393, 1991
PubMed: 1942057 (PDB entries with the same primary citation)
DOI: 10.1016/0022-2836(91)80132-E
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers431.8%16.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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