6PXQ

Crystal structure of human thrombin mutant D194A

Summary for 6PXQ

• Entry DOI: 10.2210/pdb6pxq/pdb
• Related: 1PPB
• Descriptor: Thrombin light chain, Thrombin heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: hydrolase, trypsin-like proteases, ionic interaction
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 33748.62

Authors

Stojanovski, B.,Chen, Z.,Koester, S.K.,Pelc, L.A.,Di Cera, E. (deposition date: 2019-07-26, release date: 2019-12-18, Last modification date: 2023-10-11)

• Primary citation: Stojanovski, B.M.,Chen, Z.,Koester, S.K.,Pelc, L.A.,Di Cera, E.; Role of the I16-D194 ionic interaction in the trypsin fold.; Sci Rep, 9:18035-18035, 2019; PubMed: 31792294; DOI: 10.1038/s41598-019-54564-6

Experimental method

X-RAY DIFFRACTION (2.8 Å)