6PXQ
Crystal structure of human thrombin mutant D194A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Thrombin light chain | polymer | 33 | 3791.2 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 2 | B | Thrombin heavy chain | polymer | 259 | 29736.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 3 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
B: 16 - 247 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 194 | Asp 567 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33527.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 33748.6 |
