1DWE
Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
Summary for 1DWE
Entry DOI | 10.2210/pdb1dwe/pdb |
Related | 1DWB 1DWC 1DWD |
Related PRD ID | PRD_000020 |
Descriptor | ALPHA-THROMBIN light chain, ALPHA-THROMBIN heavy chain, HIRUDIN IIIA, ... (5 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor |
Biological source | Hirudo medicinalis (Medicinal leech) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28507 |
Total number of polymer chains | 3 |
Total formula weight | 35742.20 |
Authors | Banner, D.W.,Hadvary, P. (deposition date: 1992-08-19, release date: 1994-01-31, Last modification date: 2024-06-05) |
Primary citation | Banner, D.W.,Hadvary, P. Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266:20085-20093, 1991 Cited by PubMed: 1939071PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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