1DWE

Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors

Summary for 1DWE

Related1DWB 1DWC 1DWD
Related PRD IDPRD_000020
DescriptorALPHA-THROMBIN light chain, ALPHA-THROMBIN heavy chain, HIRUDIN IIIA, ... (5 entities in total)
Functional Keywordshydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor
Biological sourceHirudo medicinalis (Medicinal leech)
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Cellular locationSecreted, extracellular space P00734 P00734
Secreted P28507
Total number of polymer chains3
Total molecular weight35742.2
Authors
Banner, D.W.,Hadvary, P. (deposition date: 1992-08-19, release date: 1994-01-31, Last modification date: 2013-02-27)
Primary citation
Banner, D.W.,Hadvary, P.
Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
J.Biol.Chem., 266:20085-20093, 1991
PubMed: 1939071 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers120.3%3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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