1DWE
Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | ALPHA-THROMBIN light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | |
2 | H | ALPHA-THROMBIN heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | |
3 | I | HIRUDIN IIIA | polymer | 11 | 1411.5 | 1 | UniProt (P28507) UniProt (by SIFTS) (P28508) In PDB | Hirudo medicinalis (Medicinal leech) | Hirudin IIIA |
4 | H | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | BIRD (PRD_000020) Chemie (0G6) | |||
5 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 35288.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 454.0 | |
All* | Total formula weight | 35742.2 |