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6CPS
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BU of 6cps by Molmil
Crystal structure of the bromodomain of human ATAD2 with a disulfide bridge
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATPase family AAA domain-containing protein 2, SULFATE ION
著者Glass, K.C, Eckenroth, B.E, Carlson, S.
登録日2018-03-14
公開日2018-12-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain.
Proteins, 87, 2019
7M97
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BU of 7m97 by Molmil
Crystal structure of the bromodomain from Plasmodium falciparum bromodomain protein 1
分子名称: Bromodomain protein 1
著者Glass, K.C.
登録日2021-03-30
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the bromodomain from Plasmodium falciparum bromodomain protein 1
To Be Published
6VEO
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BU of 6veo by Molmil
ATAD2B bromodomain in complex with 4-({[(3R,4R)-4-{[3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl]amino}piperidin-3-yl]oxy}methyl)-1lambda~6~-thiane-1,1-dione (compound 38)
分子名称: 4-({[(3R,4R)-4-{[3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl]amino}piperidin-3-yl]oxy}methyl)-1lambda~6~-thiane-1,1-dione, ATPase family AAA domain-containing protein 2B, SULFATE ION
著者Glass, K.C.
登録日2020-01-02
公開日2020-10-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain.
J.Med.Chem., 63, 2020
3MDF
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BU of 3mdf by Molmil
Crystal structure of the RRM domain of Cyclophilin 33
分子名称: Peptidyl-prolyl cis-trans isomerase E
著者Hom, R.A, Chang, P.Y, Roy, S, Mussleman, C.A, Glass, K.C, Seleznevia, A.I, Gozani, O, Ismagilov, R.F, Cleary, M.L, Kutateladze, T.G.
登録日2010-03-30
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.
J.Mol.Biol., 400, 2010
7M98
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BU of 7m98 by Molmil
ATAD2 bromodomain complexed with histone H4K5ac (res 1-10) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Phillips, M, Nix, J.C, Glass, K.C.
登録日2021-03-30
公開日2021-09-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain.
Int J Mol Sci, 22, 2021
8SDQ
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BU of 8sdq by Molmil
ATAD2 bromodomain in complex with H4S1phK5ac (res 1-15) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Nix, J.C, Glass, K.C.
登録日2023-04-07
公開日2024-06-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8SDO
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BU of 8sdo by Molmil
ATAD2 bromodomain in complex with "oncohistone" mutation H4S1CK5ac (res 1-15) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Nix, J.C, Glass, K.C.
登録日2023-04-07
公開日2024-06-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8SDX
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BU of 8sdx by Molmil
ATAD2B bromodomain in complex with histone H4 acetylated at lysine 5 with Serine 1 mutation to Cysteine
分子名称: ATPase family AAA domain-containing protein 2B, SULFATE ION, histone H4S1CK5ac
著者Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C.
登録日2023-04-07
公開日2024-06-05
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8UHL
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BU of 8uhl by Molmil
ATAD2B bromodomain in complex with histone H4 acetylated at lysine 12
分子名称: ATPase family AAA domain-containing protein 2B, Histone H4
著者Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C.
登録日2023-10-09
公開日2024-06-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8UK5
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BU of 8uk5 by Molmil
Crystal structure of the bromodomain of human ATAD2B in complex with histone H4S1(ph)K5ac
分子名称: ATPase family AAA domain-containing protein 2B, Histone H4S1(ph)K5ac
著者Montgomery, C, Phillips, M, Nix, J.C, Glass, K.C.
登録日2023-10-12
公開日2024-06-05
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
4QYD
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BU of 4qyd by Molmil
Crystal Structure of the human BRPF1 bromodomain in complex with a histone H4K12ac peptide
分子名称: Histone H4, Peregrin
著者Lubula, M.Y, Glass, K.C.
登録日2014-07-24
公開日2014-09-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain.
Febs Lett., 588, 2014
4QYL
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BU of 4qyl by Molmil
Crystal Structure of the human BRPF1 bromodomain in complex with a histone H2AK5ac peptide
分子名称: Histone H2A type 1, Peregrin, SULFATE ION
著者Lubula, M.Y, Glass, K.C.
登録日2014-07-24
公開日2014-09-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain.
Febs Lett., 588, 2014
3LH0
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BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
分子名称: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-21
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGF
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BU of 3lgf by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2
分子名称: DIMETHYLATED p53 Lysine 370 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-20
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGL
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BU of 3lgl by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K382me2
分子名称: DIMETHYLATED p53 LYSINE 382 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-20
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
6VLT
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BU of 6vlt by Molmil
Crystal Structure of Human P450 2C9*2 Genetic Variant in Complex with Losartan
分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Shah, M.B.
登録日2020-01-25
公開日2020-09-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Structure of Cytochrome P450 2C9*2 in Complex with Losartan: Insights into the Effect of Genetic Polymorphism.
Mol.Pharmacol., 98, 2020
7RL2
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BU of 7rl2 by Molmil
Crystal Structure of the Human Cytochrome P450 2C9*8 (CYP2C9*8) Genetic Variant in Complex with the Drug Losartan
分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
著者Shah, M.B.
登録日2021-07-23
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Insights into the Genetic Variations of Human Cytochrome P450 2C9: Structural Analysis, Characterization and Comparison.
Int J Mol Sci, 22, 2021
8VX0
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BU of 8vx0 by Molmil
CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN
分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
著者Shah, M.B.
登録日2024-02-02
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan.
J.Inorg.Biochem., 258, 2024
8VZ7
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BU of 8vz7 by Molmil
Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan
分子名称: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Shah, M.B.
登録日2024-02-11
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan.
J.Inorg.Biochem., 258, 2024

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