6CPS

Crystal structure of the bromodomain of human ATAD2 with a disulfide bridge

Summary for 6CPS

Entry DOI	10.2210/pdb6cps/pdb
Descriptor	ATPase family AAA domain-containing protein 2, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	disulfide bridge, bromodomain, epigenetics, chromatin reader domain, protein binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	15933.00
Authors	Glass, K.C.,Eckenroth, B.E.,Carlson, S. (deposition date: 2018-03-14, release date: 2018-12-19, Last modification date: 2023-10-04)
Primary citation	Gay, J.C.,Eckenroth, B.E.,Evans, C.M.,Langini, C.,Carlson, S.,Lloyd, J.T.,Caflisch, A.,Glass, K.C. Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain. Proteins, 87:157-167, 2019 Cited by PubMed: 30520161 DOI: 10.1002/prot.25636 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation