3LGL

Crystal structure of the 53BP1 tandem tudor domain in complex with p53K382me2

Summary for 3LGL

Related3LGF 3LH0
DescriptorTumor suppressor p53-binding protein 1, DIMETHYLATED p53 LYSINE 382 PEPTIDE, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywordstandem tudor domain, dimethylated p53 peptide, dna repair, cell cycle, dna damage, dna-binding, methylation, transcription, transcription regulation
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus Q12888
Total number of polymer chains2
Total molecular weight15684.83
Authors
Roy, S.,Kutateladze, T.G. (deposition date: 2010-01-20, release date: 2010-03-23, Last modification date: 2011-07-13)
Primary citation
Roy, S.,Musselman, C.A.,Kachirskaia, I.,Hayashi, R.,Glass, K.C.,Nix, J.C.,Gozani, O.,Appella, E.,Kutateladze, T.G.
Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398:489-496, 2010
PubMed: 20307547 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2010.03.024
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2421707.0%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report