3LGF

Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2

Summary for 3LGF

Entry DOI	10.2210/pdb3lgf/pdb
Related	3LGL 3LH0
Descriptor	Tumor suppressor p53-binding protein 1, DIMETHYLATED p53 Lysine 370 PEPTIDE, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	tandem tudor domains, dimethylated p53 peptide, dna repair, cell cycle, dna damage, dna-binding, methylation, transcription, transcription regulation
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q12888
Total number of polymer chains	2
Total formula weight	15556.57
Authors	Roy, S.,Kutateladze, T.G. (deposition date: 2010-01-20, release date: 2010-03-23, Last modification date: 2023-09-06)
Primary citation	Roy, S.,Musselman, C.A.,Kachirskaia, I.,Hayashi, R.,Glass, K.C.,Nix, J.C.,Gozani, O.,Appella, E.,Kutateladze, T.G. Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J.Mol.Biol., 398:489-496, 2010 Cited by PubMed: 20307547 DOI: 10.1016/j.jmb.2010.03.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation