3LGF
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PGE A 201 |
| Chain | Residue |
| A | HOH97 |
| A | HOH110 |
| A | HOH110 |
| A | HOH137 |
| A | HOH143 |
| A | LEU1534 |
| A | GLN1599 |
| A | GLN1599 |
| A | GLY1601 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 202 |
| Chain | Residue |
| A | LYS1514 |
| A | LEU1528 |
| A | ARG1562 |
| A | GLU1564 |
| A | TYR1569 |
| A | TRP1580 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | HOH136 |
| A | LYS1559 |
| A | LYS1563 |
| A | SER1565 |
| A | GLU1573 |
| A | ARG1578 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Region: {"description":"Interaction with dimethylated histone H4","evidences":[{"source":"PubMed","id":"17190600","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
