8SDX
ATAD2B bromodomain in complex with histone H4 acetylated at lysine 5 with Serine 1 mutation to Cysteine
Summary for 8SDX
Entry DOI | 10.2210/pdb8sdx/pdb |
Descriptor | ATPase family AAA domain-containing protein 2B, histone H4S1CK5ac, SULFATE ION, ... (4 entities in total) |
Functional Keywords | bromodomains, epigenetics, chromatin reader domain, protein binding, nuclear protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 34443.39 |
Authors | Phillips, M.,Montgomery, C.,Nix, J.C.,Glass, K.C. (deposition date: 2023-04-07, release date: 2024-06-05) |
Primary citation | Phillips, M.,Malone, K.L.,Boyle, B.W.,Montgomery, C.,Kressy, I.A.,Joseph, F.M.,Bright, K.M.,Boyson, S.P.,Chang, S.,Nix, J.C.,Young, N.L.,Jeffers, V.,Frietze, S.,Glass, K.C. Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67:8186-8200, 2024 Cited by PubMed: 38733345DOI: 10.1021/acs.jmedchem.4c00210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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