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4ZS2
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BU of 4zs2 by Molmil
Structural complex of FTO/fluorescein
分子名称: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ...
著者Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X.
登録日2015-05-13
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
8IJ1
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BU of 8ij1 by Molmil
Protomer 1 and 2 of the asymmetry trimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complex
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
著者Dai, Z, Liang, L, Yin, Y.X.
登録日2023-02-24
公開日2024-02-28
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
5OLP
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BU of 5olp by Molmil
Galacturonidase
分子名称: CALCIUM ION, Pectate lyase
著者Basle, A, Luis, A.S, Gilbert, H.J.
登録日2017-07-28
公開日2017-11-29
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides.
Nat Microbiol, 3, 2018
7WRH
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BU of 7wrh by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
著者Han, P, Xie, Y, Qi, J.
登録日2022-01-26
公開日2023-02-01
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
5OLS
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BU of 5ols by Molmil
Rhamnogalacturonan lyase
分子名称: 4-deoxy-beta-L-threo-hex-4-enopyranuronic acid-(1-2)-alpha-L-rhamnopyranose-(1-4)-beta-D-galactopyranuronic acid, CALCIUM ION, Rhamnogalacturonan lyase, ...
著者Basle, A, Luis, A.S, Gilbert, H.J.
登録日2017-07-28
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides.
Nat Microbiol, 3, 2018
2K8H
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BU of 2k8h by Molmil
Solution structure of SUMO from Trypanosoma brucei
分子名称: Small ubiquitin protein
著者Shang, Q, Tu, X.
登録日2008-09-10
公開日2009-04-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of SUMO from Trypanosoma brucei and its interaction with Ubc9
Proteins, 76, 2009
2L42
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BU of 2l42 by Molmil
The solution structure of Rap1 BRCT domain from Saccharomyces cerevisiae
分子名称: DNA-binding protein RAP1
著者Zhang, W, Zhang, J, Tu, X.
登録日2010-09-29
公開日2011-01-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of Rap1 BRCT domain from Saccharomyces cerevisiae reveals a novel fold
Biochem.Biophys.Res.Commun., 404, 2011
2L7E
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BU of 2l7e by Molmil
The structure of a domain from yeast
分子名称: Transcription initiation factor TFIID subunit 14
著者Zhang, W, Zhang, J, Tu, X.
登録日2010-12-08
公開日2011-03-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献solution structure of Taf14 YEATS domain
To be Published
4LX4
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BU of 4lx4 by Molmil
Crystal Structure Determination of Pseudomonas stutzeri endoglucanase Cel5A using a Twinned Data Set
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglucanase(Endo-1,4-beta-glucanase)protein
著者Dutoit, R, Delsaute, M, Berlemont, R, Van Elder, D, Galleni, M, Bauvois, C.
登録日2013-07-29
公開日2014-07-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.556 Å)
主引用文献Crystal structure determination of Pseudomonas stutzeri A1501 endoglucanase Cel5A: the search for a molecular basis for glycosynthesis in GH5_5 enzymes.
Acta Crystallogr D Struct Biol, 75, 2019
4EMP
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BU of 4emp by Molmil
Crystal structure of the mutant of ClpP E137A from Staphylococcus aureus
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Ye, F, Zhang, J, Liu, H, Luo, C, Yang, C.-G.
登録日2012-04-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Helix unfolding/refolding characterizes the functional dynamics of Staphylococcus aureus Clp protease
J.Biol.Chem., 288, 2013
4EMM
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Crystal structure of Staphylococcus aureus ClpP in compact conformation
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Zhang, J, Liu, H, Yang, C.-G.
登録日2012-04-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Helix unfolding/refolding characterizes the functional dynamics of Staphylococcus aureus Clp protease
J.Biol.Chem., 288, 2013
6M3C
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hAPC-h1573 Fab complex
分子名称: Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, h1573 Fab H chain, ...
著者Wang, X, Wang, D, Zhao, X, Egner, U.
登録日2020-03-03
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia.
Nat Commun, 11, 2020
4R28
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BU of 4r28 by Molmil
MspJI Restriction Endonuclease in Complex with 27-mer Oligonucleotide
分子名称: DNA (25-MER), DNA (26-MER), Restriction endonuclease
著者Horton, J.R, Cheng, X.
登録日2014-08-10
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.055 Å)
主引用文献Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.
Nucleic Acids Res., 42, 2014
6M3B
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BU of 6m3b by Molmil
hAPC-c25k23 Fab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, ...
著者Wang, X, Li, L, Zhao, X, Egner, U.
登録日2020-03-03
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia.
Nat Commun, 11, 2020
2IIT
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BU of 2iit by Molmil
Human dipeptidyl peptidase 4 in complex with a diazepan-2-one inhibitor
分子名称: (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scapin, G, Biftu, T, Weber, A.E.
登録日2006-09-28
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem.Lett., 17, 2007
5GZN
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BU of 5gzn by Molmil
Structure of neutralizing antibody bound to Zika envelope protein
分子名称: Antibody Heavy chain, Antibody light chain, Genome polyprotein
著者Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F.
登録日2016-09-29
公開日2016-12-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5Y5W
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BU of 5y5w by Molmil
Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide
分子名称: Histone peptide H4K20(me3), Spindlin-1
著者Wang, C, Zang, J.
登録日2017-08-10
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail
FEBS Lett., 592, 2018
7E3J
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BU of 7e3j by Molmil
Crystal structure of SARS-CoV-2 RBD binding to dog ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE2, Spike protein S1, ...
著者Zhang, Z, Zhang, Y.
登録日2021-02-08
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The molecular basis for SARS-CoV-2 binding to dog ACE2.
Nat Commun, 12, 2021
2IIV
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BU of 2iiv by Molmil
Human dipeptidyl peptidase 4 in complex with a diazepan-2-one inhibitor
分子名称: (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scapin, G, Weber, A.E, Biftu, T.
登録日2006-09-28
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem.Lett., 17, 2007
2AOU
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Histamine Methyltransferase Complexed with the Antimalarial Drug Amodiaquine
分子名称: 4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL, Histamine N-methyltransferase
著者Horton, J.R, Sawada, K, Nishibori, M, Cheng, X.
登録日2005-08-14
公開日2005-09-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
2AOX
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Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine
分子名称: Histamine N-methyltransferase, TACRINE
著者Horton, J.R, Sawada, K, Nishibori, M, Cheng, X.
登録日2005-08-14
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
2AOV
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Histamine Methyltransferase Complexed with the Antifolate Drug Metoprine
分子名称: 4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE, 5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAMINE, Histamine N-methyltransferase
著者Horton, J.R, Sawada, K, Nishibori, M, Cheng, X.
登録日2005-08-14
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
5GZO
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BU of 5gzo by Molmil
Structure of neutralizing antibody bound to Zika envelope protein
分子名称: Antibody heavy chain, Antibody light chain, Genome polyprotein
著者Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F.
登録日2016-09-29
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.755 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5DZN
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human T-cell immunoglobulin and mucin domain protein 4
分子名称: T-cell immunoglobulin and mucin domain-containing protein 4
著者Yuan, S, Rao, Z, Wang, X.
登録日2015-09-25
公開日2015-11-25
最終更新日2016-02-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope.
Protein Cell, 6, 2015
1XMZ
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Crystal structure of the dark state of kindling fluorescent protein kfp from anemonia sulcata
分子名称: BETA-MERCAPTOETHANOL, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2
著者Quillin, M.L, Anstrom, D.M, Shu, X, O'Leary, S, Kallio, K, Chudakov, D.M, Remington, S.J.
登録日2004-10-04
公開日2005-04-19
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Kindling Fluorescent Protein from Anemonia sulcata: Dark-State Structure at 1.38 Resolution
Biochemistry, 44, 2005

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