4ZS2

Structural complex of FTO/fluorescein

Summary for 4ZS2

Entry DOI	10.2210/pdb4zs2/pdb
Related	4ZS3
Descriptor	Alpha-ketoglutarate-dependent dioxygenase FTO, 2-OXOGLUTARIC ACID, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, ... (5 entities in total)
Functional Keywords	inhibitor, fluorescein, fluorescent protein-inhibitor complex, fluorescent protein/inhibitor
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : Q9C0B1
Total number of polymer chains	1
Total formula weight	55467.31
Authors	Wang, T.,Hong, T.,Huang, Y.,Yang, C.G.,Zhou, X. (deposition date: 2015-05-13, release date: 2015-11-04, Last modification date: 2015-11-18)
Primary citation	Wang, T.,Hong, T.,Huang, Y.,Su, H.,Wu, F.,Chen, Y.,Wei, L.,Huang, W.,Hua, X.,Xia, Y.,Xu, J.,Gan, J.,Yuan, B.,Feng, Y.,Zhang, X.,Yang, C.G.,Zhou, X. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137:13736-13739, 2015 Cited by PubMed: 26457839 DOI: 10.1021/jacs.5b06690 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation