4R28

MspJI Restriction Endonuclease in Complex with 27-mer Oligonucleotide

Summary for 4R28

Entry DOI	10.2210/pdb4r28/pdb
Related	4F0P 4F0Q
Descriptor	Restriction endonuclease, DNA (25-MER), DNA (26-MER) (3 entities in total)
Functional Keywords	endonuclease, dna methylation dependent, sra domain, epigenetics tool, cytosine methylation-dependent endonuclease, tetrameric endonuclease, hydrolase, hydrolase-dna complex, hydrolase/dna
Biological source	Mycobacterium sp. JLS More
Total number of polymer chains	6
Total formula weight	215774.68
Authors	Horton, J.R.,Cheng, X. (deposition date: 2014-08-10, release date: 2014-10-08, Last modification date: 2023-09-20)
Primary citation	Horton, J.R.,Wang, H.,Mabuchi, M.Y.,Zhang, X.,Roberts, R.J.,Zheng, Y.,Wilson, G.G.,Cheng, X. Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix. Nucleic Acids Res., 42:12092-12101, 2014 Cited by PubMed: 25262349 DOI: 10.1093/nar/gku871 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.055 Å)

Structure validation