Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6WF5
DownloadVisualize
BU of 6wf5 by Molmil
Crystal structure of human Naa50 in complex with a truncated cofactor derived inhibitor (compound 2)
分子名称: (2R)-2-hydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide, ACE-MET-LEU-GLY-PRO-NH2, N-alpha-acetyltransferase 50
著者Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E.
登録日2020-04-03
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
6WFG
DownloadVisualize
BU of 6wfg by Molmil
Crystal structure of human Naa50 in complex with an inhibitor (compound 3) identified using DNA encoded library technology
分子名称: (2S)-N-[(2S)-3-[1-(3-tert-butyl-1-methyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1-(methylamino)-1-oxopropan-2-yl]-6-oxopiperidine-2-carboxamide, COENZYME A, N-alpha-acetyltransferase 50
著者Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E.
登録日2020-04-03
公開日2020-07-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
6WFO
DownloadVisualize
BU of 6wfo by Molmil
Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4b) identified using DNA encoded library technology
分子名称: (4S)-1-methyl-N-{(3S,5R)-5-[4-(methylcarbamoyl)-1,3-thiazol-2-yl]-1-[4-(1H-tetrazol-5-yl)benzene-1-carbonyl]pyrrolidin-3-yl}-2,6-dioxohexahydropyrimidine-4-carboxamide, ACETYL COENZYME *A, N-alpha-acetyltransferase 50
著者Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E.
登録日2020-04-03
公開日2020-07-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
6WF3
DownloadVisualize
BU of 6wf3 by Molmil
Crystal structure of human Naa50 in complex with a cofactor derived inhibitor (compound 1)
分子名称: ACE-MET-LEU-GLY-PRO-NH2, COENZYME A, N-alpha-acetyltransferase 50
著者Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E.
登録日2020-04-03
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Acs Med.Chem.Lett., 11, 2020
7LQK
DownloadVisualize
BU of 7lqk by Molmil
Crystal structure of the R375A mutant of LeuT
分子名称: ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ...
著者Font, J, Aguilar, J, Galli, A, Ryan, R.
登録日2021-02-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
7LQJ
DownloadVisualize
BU of 7lqj by Molmil
Crystal structure of LeuT bound to L-Alanine
分子名称: ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ...
著者Font, J, Aguilar, J, Galli, A, Ryan, R.
登録日2021-02-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
7LQL
DownloadVisualize
BU of 7lql by Molmil
Crystal structure of the R375D mutant of LeuT
分子名称: ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ...
著者Font, J, Aguilar, J, Galli, A, Ryan, R.
登録日2021-02-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
6GK8
DownloadVisualize
BU of 6gk8 by Molmil
Crystal structure of anti-tau antibody dmCBTAU-28.1, double mutant (S32R, E35K) of CBTAU-28.1, in complex with Tau peptide A7731 (residues 52-71)
分子名称: CHLORIDE ION, HUMAN FAB ANTIBODY FRAGMENT OF CBTAU-28.1(S32R;E35K), TAU PEPTIDE A7731 (RESIDUES 52-71)
著者Steinbacher, S, Mrosek, M, Juraszek, J.
登録日2018-05-18
公開日2018-06-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
6GK7
DownloadVisualize
BU of 6gk7 by Molmil
Crystal structure of anti-tau antibody dmCBTAU-27.1, double mutant (S31Y, T100I) of CBTAU-27.1, in complex with Tau peptide A8119B (residues 299-318)
分子名称: CHLORIDE ION, HUMAN FAB ANTIBODY FRAGMENT OF CBTAU-27.1(S31Y,T100I), HUMAN TAU PEPTIDE A8119 RESIDUES 299-318
著者Steinbacher, S, Mrosek, M, Juraszek, J.
登録日2018-05-18
公開日2018-06-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
5ZV3
DownloadVisualize
BU of 5zv3 by Molmil
Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide
分子名称: Heavy chain of antibody CBTAU28.1, Light chain (kappa) of antibody CBTAU28.1, Peptide from Microtubule-associated protein tau
著者Zhang, H, Wilson, I.A.
登録日2018-05-09
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
3B64
DownloadVisualize
BU of 3b64 by Molmil
Macrophage Migration Inhibitory Factor (MIF) From /Leishmania Major
分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor-like protein
著者Zierow, S, Cho, Y, Lolis, E.
登録日2007-10-27
公開日2008-06-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献A leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses.
J.Immunol., 180, 2008
5V7R
DownloadVisualize
BU of 5v7r by Molmil
Cyrstal structure of anti-Tau antibody CBTAU-7.1 Fab
分子名称: CBTAU-7.1 Fab heavy chain, CBTAU-7.1 Fab light chain
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2017-03-20
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Immunological memory to hyperphosphorylated tau in asymptomatic individuals.
Acta Neuropathol., 133, 2017
5JRP
DownloadVisualize
BU of 5jrp by Molmil
crystal structure of monoclonal antibody MR78 Fab
分子名称: SODIUM ION, marberg virus monoclonal antibody MR78 Fab heavy chain, marberg virus monoclonal antibody MR78 Fab light chain
著者Dong, J, Crowe, J.
登録日2016-05-06
公開日2017-11-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
4ZV6
DownloadVisualize
BU of 4zv6 by Molmil
Crystal structure of the artificial alpharep-7 octarellinV.1 complex
分子名称: AlphaRep-7, Octarellin V.1
著者Figueroa, M, Sleutel, M, Urvoas, A, Valerio-Lepiniec, M, Minard, P, Martial, J.A, van de Weerdt, C.
登録日2015-05-18
公開日2016-05-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
7QOX
DownloadVisualize
BU of 7qox by Molmil
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J.
登録日2021-12-29
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
7QOT
DownloadVisualize
BU of 7qot by Molmil
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIa heavy chain, Kininogen-1 light chain, ...
著者Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J.
登録日2021-12-28
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
5BOP
DownloadVisualize
BU of 5bop by Molmil
Crystal structure of the artificial nanobody octarellinV.1 complex
分子名称: Nanobody, Octarellin V.1
著者Figueroa, M, Sleutel, M, Pardon, E, Steyaert, J, Martial, J.A, van de Weerdt, C.
登録日2015-05-27
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
6DCW
DownloadVisualize
BU of 6dcw by Molmil
Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide
分子名称: Heavy chain of CBTAU27.1 Fab, Light chain of CBTAU27.1 Fab, tau peptide
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2018-05-08
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
5WEQ
DownloadVisualize
BU of 5weq by Molmil
The crystal structure of a MR78 mutant
分子名称: MR78 mutant Fab heavy chain, MR78 mutant light chain
著者Dong, J, Williamson, L.E, Crowe, J.E.
登録日2017-07-10
公開日2018-04-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
6DCV
DownloadVisualize
BU of 6dcv by Molmil
Crystal structure of human anti-tau antibody CBTAU-27.1
分子名称: GLYCEROL, Light chain of CBTAU27.1 Fab, heavy chain of CBTAU-27.1 Fab
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2018-05-08
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
1BH1
DownloadVisualize
BU of 1bh1 by Molmil
STRUCTURAL STUDIES OF D-PRO MELITTIN, NMR, 20 STRUCTURES
分子名称: MELITTIN
著者Barnham, K.J, Hewish, D, Werkmeister, J, Curtain, C, Kirkpatrick, A, Bartone, N, Liu, S.T, Norton, R, Rivett, D.
登録日1998-06-11
公開日1999-01-06
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Structure and activity of D-Pro14 melittin.
J.Protein Chem., 21, 2002
6H06
DownloadVisualize
BU of 6h06 by Molmil
FAB CBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-5
分子名称: GLYCEROL, HUMAN FAB ANTIBODY FRAGMENT OF CBTAU-22.1, HUMAN FAB ANTIBODY FRAGMENT OF HCBTAU-22.1, ...
著者Juraszek, J, Steinbacher, S.
登録日2018-07-06
公開日2018-07-25
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422containing epitope on pathological tau.
Acta Neuropathol Commun, 6, 2018
6H0E
DownloadVisualize
BU of 6h0e by Molmil
FAB dmCBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-23
分子名称: GLYCEROL, HUMAN FAB ANTIBODY FRAGMENT OF dmCBTAU-22.1, Microtubule-associated protein tau
著者Juraszek, J, Steinbacher, S.
登録日2018-07-09
公開日2018-07-25
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422containing epitope on pathological tau.
Acta Neuropathol Commun, 6, 2018
4DAW
DownloadVisualize
BU of 4daw by Molmil
Crystal structure of PAK1 kinase domain with the ruthenium phthalimide complex
分子名称: Serine/threonine-protein kinase PAK 1, [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium
著者Maksimoska, J, Marmorstein, R.
登録日2012-01-13
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The art of filling protein pockets efficiently with octahedral metal complexes.
Angew.Chem.Int.Ed.Engl., 51, 2012
6DL8
DownloadVisualize
BU of 6dl8 by Molmil
Crystal Structure of an influenza A hemagglutinin antibody Fab variant CH67:1203d4 chimera
分子名称: CH67:1203d4 FAB light chain, Ch67:1203d4 FAB heavy chain
著者Dong, J, Finn, J.A, Crowe, J.E.
登録日2018-05-31
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.805 Å)
主引用文献Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Structure, 28, 2020

221716

件を2024-06-26に公開中

PDB statisticsPDBj update infoContact PDBjnumon