3B9S

Macrophage Migration Inhibitory Factor (MIF) complexed with Inhibitor, 4-IPP.

Summary for 3B9S

• Entry DOI: 10.2210/pdb3b9s/pdb
• Related: 1MIF
• Descriptor: Macrophage Migration Inhibitory Factor, GLYCEROL, 4-phenylpyrimidine, ... (5 entities in total)
• Functional Keywords: macrophage migration inhibitory factor, cytokine
• Biological source: Homo sapiens
• Cellular location: Secreted : P14174
• Total number of polymer chains: 3
• Total formula weight: 38194.25

Authors

Zierow, S.,Crichlow, G.,Lolis, E. (deposition date: 2007-11-06, release date: 2008-09-23, Last modification date: 2023-08-30)

• Primary citation: Winner, M.,Meier, J.,Zierow, S.,Rendon, B.E.,Crichlow, G.V.,Riggs, R.,Bucala, R.,Leng, L.,Smith, N.,Lolis, E.,Trent, J.O.,Mitchell, R.A.; A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.; Cancer Res., 68:7253-7257, 2008; PubMed: 18794110; DOI: 10.1158/0008-5472.CAN-07-6227

Experimental method

X-RAY DIFFRACTION (1.8 Å)