7LQL

Crystal structure of the R375D mutant of LeuT

Summary for 7LQL

Entry DOI	10.2210/pdb7lql/pdb
Related	6W95 6W99
Descriptor	Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ALANINE, ... (5 entities in total)
Functional Keywords	transporter, leucine transporter, transport protein
Biological source	Aquifex aeolicus (strain VF5)
Total number of polymer chains	1
Total formula weight	59339.88
Authors	Font, J.,Aguilar, J.,Galli, A.,Ryan, R. (deposition date: 2021-02-13, release date: 2021-05-19, Last modification date: 2023-10-18)
Primary citation	Aguilar, J.I.,Cheng, M.H.,Font, J.,Schwartz, A.C.,Ledwitch, K.,Duran, A.,Mabry, S.J.,Belovich, A.N.,Zhu, Y.,Carter, A.M.,Shi, L.,Kurian, M.A.,Fenollar-Ferrer, C.,Meiler, J.,Ryan, R.M.,Mchaourab, H.S.,Bahar, I.,Matthies, H.J.,Galli, A. Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia. Elife, 10:-, 2021 Cited by PubMed: 34002696 DOI: 10.7554/eLife.68039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation