7LQL
Crystal structure of the R375D mutant of LeuT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Na(+):neurotransmitter symporter (Snf family) | polymer | 519 | 58035.3 | 1 | UniProt (O67854) Pfam (PF00209) | Aquifex aeolicus (strain VF5) | |
| 2 | B, C (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D (A) | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
| 4 | E, F, G, H (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 4 | Chemie (BOG) | |||
| 5 | I (A) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 1 - 513 (UniProt: O67854)
| PDB | External Database | Details |
|---|---|---|
| Asp 375 | Arg 375 | engineered mutation |
| Gly 514 | - | expression tag |
| Thr 515 | - | expression tag |
| Leu 516 | - | expression tag |
| Val 517 | - | expression tag |
| Pro 518 | - | expression tag |
| Arg 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58035.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1304.5 | |
| All* | Total formula weight | 59339.9 |
