5UFU
Structure of AMPK bound to activator
Summary for 5UFU
Entry DOI | 10.2210/pdb5ufu/pdb |
Descriptor | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... (9 entities in total) |
Functional Keywords | kinase, ampk, activator, allostery, transferase-activator complex, transferase/activator |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm : Q5EG47 |
Total number of polymer chains | 3 |
Total formula weight | 120588.06 |
Authors | |
Primary citation | Cokorinos, E.C.,Delmore, J.,Reyes, A.R.,Albuquerque, B.,Kjbsted, R.,Jrgensen, N.O.,Tran, J.L.,Jatkar, A.,Cialdea, K.,Esquejo, R.M.,Meissen, J.,Calabrese, M.F.,Cordes, J.,Moccia, R.,Tess, D.,Salatto, C.T.,Coskran, T.M.,Opsahl, A.C.,Flynn, D.,Blatnik, M.,Li, W.,Kindt, E.,Foretz, M.,Viollet, B.,Ward, J.,Kurumbail, R.G.,Kalgutkar, A.S.,Wojtaszewski, J.F.P.,Cameron, K.O.,Miller, R.A. Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. Cell Metab., 25:1147-1159.e10, 2017 Cited by PubMed: 28467931DOI: 10.1016/j.cmet.2017.04.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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