crystal structure of monoclonal antibody MR78 Fab

Summary for 5JRP

Descriptormarberg virus monoclonal antibody MR78 Fab light chain, marberg virus monoclonal antibody MR78 Fab heavy chain, SODIUM ION, ... (4 entities in total)
Functional Keywordsmarberg virus, monoclonal antibody, immune system
Biological sourceHomo sapiens
Total number of polymer chains2
Total molecular weight47257.5
Dong, J.,Crowe, J. (deposition date: 2016-05-06, release date: 2017-11-08, Last modification date: 2018-04-25)
Primary citation
Sangha, A.K.,Dong, J.,Williamson, L.,Hashiguchi, T.,Saphire, E.O.,Crowe, J.E.,Meiler, J.
Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25:1820-1828.e2, 2017
PubMed: 29153506 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2017.10.005
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1952000.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution