5V7U
Cyrstal structure of anti-Tau antibody CBTAU-22.1 Fab
Summary for 5V7U
Entry DOI | 10.2210/pdb5v7u/pdb |
Related | 5V7R |
Descriptor | CBTAU-22.1 Fab light chain, CBTAU-22.1 Fab heavy chain, SULFATE ION, ... (4 entities in total) |
Functional Keywords | antibody, fab, tau protein, alzheimer's disease, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 48173.88 |
Authors | Zhu, X.,Zhang, H.,Wilson, I.A. (deposition date: 2017-03-20, release date: 2017-04-12, Last modification date: 2023-10-04) |
Primary citation | Pascual, G.,Wadia, J.S.,Zhu, X.,Keogh, E.,Kukrer, B.,van Ameijde, J.,Inganas, H.,Siregar, B.,Perdok, G.,Diefenbach, O.,Nahar, T.,Sprengers, I.,Koldijk, M.H.,der Linden, E.C.,Peferoen, L.A.,Zhang, H.,Yu, W.,Li, X.,Wagner, M.,Moreno, V.,Kim, J.,Costa, M.,West, K.,Fulton, Z.,Chammas, L.,Luckashenak, N.,Fletcher, L.,Holland, T.,Arnold, C.,Anthony Williamson, R.,Hoozemans, J.J.,Apetri, A.,Bard, F.,Wilson, I.A.,Koudstaal, W.,Goudsmit, J. Immunological memory to hyperphosphorylated tau in asymptomatic individuals. Acta Neuropathol., 133:767-783, 2017 Cited by PubMed: 28341999DOI: 10.1007/s00401-017-1705-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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