6H0E
FAB dmCBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-23
Summary for 6H0E
Entry DOI | 10.2210/pdb6h0e/pdb |
Descriptor | HUMAN FAB ANTIBODY FRAGMENT OF dmCBTAU-22.1, Microtubule-associated protein tau, GLYCEROL, ... (5 entities in total) |
Functional Keywords | fab, tau peptide, complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 202205.56 |
Authors | Juraszek, J.,Steinbacher, S. (deposition date: 2018-07-09, release date: 2018-07-25, Last modification date: 2020-03-11) |
Primary citation | van Ameijde, J.,Crespo, R.,Janson, R.,Juraszek, J.,Siregar, B.,Verveen, H.,Sprengers, I.,Nahar, T.,Hoozemans, J.J.,Steinbacher, S.,Willems, R.,Delbroek, L.,Borgers, M.,Dockx, K.,Van Kolen, K.,Mercken, M.,Pascual, G.,Koudstaal, W.,Apetri, A. Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422containing epitope on pathological tau. Acta Neuropathol Commun, 6:59-59, 2018 Cited by PubMed: 30001207DOI: 10.1186/s40478-018-0562-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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