6P9H

Crystal structure of human anti staphylococcus aureus antibody STAU-281 Fab in complex with IsdB NEAT2 domain

Summary for 6P9H

• Entry DOI: 10.2210/pdb6p9h/pdb
• Descriptor: Iron-regulated heme-iron binding protein, Human anti staphylococcus aureus antibody STAU-281 Fab heavy chain, Human anti staphylococcus aureus antibody STAU-281 Fab light chain, ... (4 entities in total)
• Functional Keywords: iron-regulated surface determinant system, isdb, neat2 domain, antibody, immune system
• Biological source: Staphylococcus aureus; More
• Total number of polymer chains: 6
• Total formula weight: 122019.09

Authors

Dong, J.,Crowe, J.E. (deposition date: 2019-06-10, release date: 2020-06-17, Last modification date: 2023-10-11)

• Primary citation: Bennett, M.R.,Dong, J.,Bombardi, R.G.,Soto, C.,Parrington, H.M.,Nargi, R.S.,Schoeder, C.T.,Nagel, M.B.,Schey, K.L.,Meiler, J.,Skaar, E.P.,Crowe Jr., J.E.; Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.; Mbio, 10:-, 2019; PubMed: 31641091; DOI: 10.1128/mBio.02473-19

Experimental method

X-RAY DIFFRACTION (3.003 Å)