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6KCT
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Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 5
分子名称: 3-(cyclohexylmethyl)-6,8-bis(oxidanyl)isochromen-1-one, LYSINE, Lysine--tRNA ligase
著者Zhou, J, Fang, P.
登録日2019-06-29
公開日2020-04-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
Acs Chem.Biol., 15, 2020
6KBF
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BU of 6kbf by Molmil
Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 3
分子名称: (3~{S})-3-[[(1~{S},3~{S})-3-methylcyclohexyl]methyl]-6,8-bis(oxidanyl)-3,4-dihydro-2~{H}-isoquinolin-1-one, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Zhou, J, Fang, P.
登録日2019-06-24
公開日2020-04-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
Acs Chem.Biol., 15, 2020
3N9T
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BU of 3n9t by Molmil
Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
分子名称: 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, CITRATE ANION, FE (III) ION, ...
著者Liu, W, Shen, W, Fang, P, Li, J, Cui, Z.
登録日2010-05-31
公開日2010-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
To be Published
3ONK
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BU of 3onk by Molmil
yeast Ent3_ENTH domain
分子名称: Epsin-3
著者Wang, J, Fang, P, Niu, L, Teng, M.
登録日2010-08-29
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
3ONL
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BU of 3onl by Molmil
yeast Ent3_ENTH-Vti1p_Habc complex structure
分子名称: Epsin-3, t-SNARE VTI1
著者Wang, J, Fang, P, Niu, L, Teng, M.
登録日2010-08-29
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
3ONJ
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Crystal structure of yeast Vti1p_Habc domain
分子名称: t-SNARE VTI1
著者Wang, J, Fang, P, Niu, L, Teng, M.
登録日2010-08-29
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
7X3O
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BU of 7x3o by Molmil
Crystal structure of Aldo-keto reductase 1C3 complexed with compound S07054
分子名称: (2~{R})-2-(3-fluoranyl-4-pyrimidin-5-yl-phenyl)butanoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Jiang, J, Liu, Y, He, S, Chen, Y, Chu, X, Liu, Y, Guo, Q, Zhao, L, Feng, F, Liu, W, Zhang, X, Fang, P, Sun, H.
登録日2022-03-01
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structure of Aldo-keto reductase 1C3 complexed with compound S07054
To Be Published
7E2M
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Crystal structure of the RWD domain of human GCN2 - 2
分子名称: eIF-2-alpha kinase GCN2
著者Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P.
登録日2021-02-05
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Biochem.Biophys.Res.Commun., 549, 2021
7E2K
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Crystal structure of the RWD domain of human GCN2 - 1
分子名称: eIF-2-alpha kinase GCN2
著者Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P.
登録日2021-02-05
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.041 Å)
主引用文献Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Biochem.Biophys.Res.Commun., 549, 2021
7EA9
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BU of 7ea9 by Molmil
Crystal Structure of human lysyl-tRNA synthetase Y145H mutant
分子名称: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, Lysine--tRNA ligase
著者Wu, S, Hei, Z, Zheng, L, Zhou, J, Liu, Z, Wang, J, Fang, P.
登録日2021-03-06
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment.
Biochem.Biophys.Res.Commun., 554, 2021
2MLK
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BU of 2mlk by Molmil
Three-dimensional structure of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae
分子名称: RstA
著者Fang, P, Chen, S, Cheng, Y, Chang, C, Yu, T, Huang, T.
登録日2014-03-02
公開日2014-07-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
6ZWJ
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BU of 6zwj by Molmil
Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution
分子名称: CITRIC ACID, GLYCEROL, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWF
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BU of 6zwf by Molmil
Neisseria gonorrhoeae transaldolase
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ...
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZX4
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BU of 6zx4 by Molmil
Neisseria gonorrhoeae transaldolase
分子名称: CITRIC ACID, GLYCEROL, Transaldolase
著者Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
登録日2020-07-29
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWH
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BU of 6zwh by Molmil
Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7B0L
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BU of 7b0l by Molmil
Neisseria gonorrhoeae transaldolase, low-dose inhouse
分子名称: CITRIC ACID, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
登録日2020-11-20
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7BBW
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BU of 7bbw by Molmil
Neisseria gonorrhoeae transaldolase, variant C38S
分子名称: GLYCEROL, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
登録日2020-12-18
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7BBX
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BU of 7bbx by Molmil
Neisseria gonorrhoeae transaldolase, variant K8A
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.M, Tittmann, K.
登録日2020-12-18
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
3SZX
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BU of 3szx by Molmil
Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
分子名称: RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
著者Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
登録日2011-07-19
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
3SYW
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Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
分子名称: PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
著者Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
登録日2011-07-18
公開日2012-04-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
5BTM
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BU of 5btm by Molmil
Crystal structure of AUUCU repeating RNA that causes spinocerebellar ataxia type 10 (SCA10)
分子名称: MAGNESIUM ION, RNA (55-mer), SODIUM ION
著者Park, H.
登録日2015-06-03
公開日2015-07-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.778 Å)
主引用文献Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10).
Biochemistry, 54, 2015
3SJ2
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BU of 3sj2 by Molmil
A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome
分子名称: ACETATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3')
著者Kumar, A, Pengfei, F, Park, H, Nettles, K, Guo, M, Disney, M.D.
登録日2011-06-20
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome.
Chembiochem, 12, 2011
7VIC
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The crystal structure of SARS-CoV-2 3C-like protease in complex with a traditional Chinese Medicine Inhibitors
分子名称: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, 3C-like proteinase
著者Zhong, B, Chen, B, Zhou, H, Sun, L.
登録日2021-09-26
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Oridonin Inhibits SARS-CoV-2 by Targeting Its 3C-Like Protease.
Small Sci, 2, 2022
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