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6J53

Crystal structure of human HINT1 complexing with ATP

Summary for 6J53
Entry DOI10.2210/pdb6j53/pdb
DescriptorHistidine triad nucleotide-binding protein 1, ADENOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywordshydrolase, nucleotide binding, regulation of transcription, signal transduction
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight28395.55
Authors
Wang, J.,Fang, P.,Guo, M. (deposition date: 2019-01-10, release date: 2019-09-25, Last modification date: 2023-11-22)
Primary citationYu, J.,Liu, Z.,Liang, Y.,Luo, F.,Zhang, J.,Tian, C.,Motzik, A.,Zheng, M.,Kang, J.,Zhong, G.,Liu, C.,Fang, P.,Guo, M.,Razin, E.,Wang, J.
Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10:4664-4664, 2019
Cited by
PubMed: 31604935
DOI: 10.1038/s41467-019-12710-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.52 Å)
Structure validation

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