6ILH

Crystal Structure of human lysyl-tRNA synthetase L350H mutant

Summary for 6ILH

• Entry DOI: 10.2210/pdb6ilh/pdb
• Related: 6ILD
• Descriptor: Lysine-tRNA ligase, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE (3 entities in total)
• Functional Keywords: lysyl-trna synthetase, lysrs, disease related mutant, ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 121621.57

Authors

Hei, Z.,Liu, Z.,Wang, J.,Fang, P. (deposition date: 2018-10-18, release date: 2019-02-27, Last modification date: 2023-11-22)

• Primary citation: Hei, Z.,Wu, S.,Liu, Z.,Wang, J.,Fang, P.; Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.; J. Biol. Chem., 294:4775-4783, 2019; PubMed: 30733335; DOI: 10.1074/jbc.RA118.006356

Experimental method

X-RAY DIFFRACTION (2.501 Å)