Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6J65

Crystal structure of human HINT1 mutant complexing with AP4A II

Summary for 6J65
Entry DOI10.2210/pdb6j65/pdb
Related5ED3 5ED6 6J53 6J58 6J5S 6J5Z 6J64
DescriptorHistidine triad nucleotide-binding protein 1, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywordshydrolase, nucleotide binding, regulation of transcription, signal transduction
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight56903.08
Authors
Wang, J.,Fang, P.,Guo, M. (deposition date: 2019-01-14, release date: 2019-09-25, Last modification date: 2023-11-22)
Primary citationYu, J.,Liu, Z.,Liang, Y.,Luo, F.,Zhang, J.,Tian, C.,Motzik, A.,Zheng, M.,Kang, J.,Zhong, G.,Liu, C.,Fang, P.,Guo, M.,Razin, E.,Wang, J.
Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.
Nat Commun, 10:4664-4664, 2019
Cited by
PubMed: 31604935
DOI: 10.1038/s41467-019-12710-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.42 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon