3OUB
 
 | | MDR769 HIV-1 protease complexed with NC/p1 hepta-peptide | | 分子名称: | MDR HIV-1 protease, NC/p1 substrate peptide | | 著者 | Liu, Z, Wang, Y, Brunzelle, J, Kovari, I.A, Kovari, L.C. | | 登録日 | 2010-09-14 | | 公開日 | 2011-03-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease.
Protein J., 30, 2011
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3OUD
 | | MDR769 HIV-1 protease complexed with CA/p2 hepta-peptide | | 分子名称: | CA/p2 substrate peptide, MDR HIV-1 protease | | 著者 | Liu, Z, Wang, Y, Brunzelle, J, Kovari, I.A, Kovari, L.C. | | 登録日 | 2010-09-14 | | 公開日 | 2011-03-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease.
Protein J., 30, 2011
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3P8E
 | | Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine | | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1S)-1-aminopentyl]-L-ornithine | | 著者 | Lluis, M, Wang, Y, Monzingo, A.F, Fast, W, Robertus, J.D. | | 登録日 | 2010-10-13 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4946 Å) | | 主引用文献 | Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1.
Chemmedchem, 6, 2011
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6JE4
 | | Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | | 分子名称: | 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.069 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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8WQR
 | | Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation | | 分子名称: | Activating molecule in BECN1-regulated autophagy protein 1, DNA damage-binding protein 1 | | 著者 | Liu, M, Wang, Y, Su, M.Y, Stjepanovic, G. | | 登録日 | 2023-10-12 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation.
Nat Commun, 14, 2023
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5E6F
 | | Canarypox virus resolvase | | 分子名称: | CNPV261 Holliday junction resolvase protein, D(-)-TARTARIC ACID, MAGNESIUM ION | | 著者 | Li, H, Hwang, Y, Perry, K, Bushman, F.D, Van Duyne, G.D. | | 登録日 | 2015-10-09 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure and Metal Binding Properties of a Poxvirus Resolvase.
J.Biol.Chem., 291, 2016
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6JFU
 | | Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) | | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target strand, ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-12 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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5Z4U
 | | Crystal Structure of T2R-TTL complex with 7a3 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(4-ethoxyphenyl)-1-methyl-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole, CALCIUM ION, ... | | 著者 | Lai, Q, Wang, Y, Yang, J, Yao, Y. | | 登録日 | 2018-01-14 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Crystal Structure of T2R-TTL complex with 7a3
To Be Published
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6KC7
 | | Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in seed-base paring state | | 分子名称: | CRISPR-associated endonuclease Cas9, DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*AP*AP*AP*GP*TP*T)-3'), ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-06-27 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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5WTJ
 | | Crystal structure of an endonuclease | | 分子名称: | CRISPR-associated endoribonuclease C2c2 | | 著者 | Liu, L, Wang, Y. | | 登録日 | 2016-12-13 | | 公開日 | 2017-02-08 | | 最終更新日 | 2017-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | | 主引用文献 | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
Cell, 168, 2017
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3B96
 | | Structural Basis for Substrate Fatty-Acyl Chain Specificity: Crystal Structure of Human Very-Long-Chain Acyl-CoA Dehydrogenase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, TETRADECANOYL-COA, Very long-chain specific acyl-CoA dehydrogenase | | 著者 | McAndrew, R.P, Wang, Y, Mohsen, A.W, He, M, Vockley, J, Kim, J.J. | | 登録日 | 2007-11-02 | | 公開日 | 2008-02-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.
J.Biol.Chem., 283, 2008
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8HNW
 | | Crystal structure of HpaCas9-sgRNA surveillance complex bound to double-stranded DNA | | 分子名称: | CRISPR-associated endonuclease Cas9, Non-target strand, Target strand, ... | | 著者 | Sun, W, Cheng, Z, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8HNS
 | | Crystal structure of an anti-CRISPR protein AcrIIC4 in apo form | | 分子名称: | GLYCEROL, anti-CRISPR protein AcrIIC4 | | 著者 | Sun, W, Cheng, Z, Yang, J, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8HNT
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8HNV
 | | CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4 | | 分子名称: | CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ... | | 著者 | Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7DRB
 | | Crystal structure of plant receptor like protein RXEG1 with xyloglucanase XEG1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | | 著者 | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | 登録日 | 2020-12-27 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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7DRC
 | | Cryo-EM structure of plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 and BAK1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinosteroid insensitive 1-associated receptor kinase 1, ... | | 著者 | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | | 登録日 | 2020-12-27 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Plant receptor-like protein activation by a microbial glycoside hydrolase.
Nature, 610, 2022
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3CIY
 | | Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R. | | 登録日 | 2008-03-12 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
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1WN0
 | | Crystal Structure of Histidine-containing Phosphotransfer Protein, ZmHP2, from maize | | 分子名称: | histidine-containing phosphotransfer protein | | 著者 | Sugawara, H, Kawano, Y, Hatakeyama, T, Yamaya, T, Kamiya, N, Sakakibara, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-07-24 | | 公開日 | 2005-01-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the histidine-containing phosphotransfer protein ZmHP2 from maize
Protein Sci., 14, 2005
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5WTK
 | | Crystal structure of RNP complex | | 分子名称: | CRISPR-associated endoribonuclease C2c2, RNA (58-MER) | | 著者 | Liu, L, Wang, Y. | | 登録日 | 2016-12-13 | | 公開日 | 2017-02-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | | 主引用文献 | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
Cell, 168, 2017
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5XWP
 | | Crystal structure of LbuCas13a-crRNA-target RNA ternary complex | | 分子名称: | RNA (30-MER), RNA (59-MER), Uncharacterized protein | | 著者 | Liu, L, Li, X, Li, Z, Wang, Y. | | 登録日 | 2017-06-30 | | 公開日 | 2017-09-13 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.086 Å) | | 主引用文献 | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
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3CIG
 | | Crystal structure of mouse TLR3 ectodomain | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R. | | 登録日 | 2008-03-11 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
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6JDV
 | | Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state | | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, MAGNESIUM ION, ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-02 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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5GQ9
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6JDQ
 | | Crystal structure of Nme1Cas9 in complex with sgRNA | | 分子名称: | CRISPR-associated endonuclease Cas9, sgRNA | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-02 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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