3CIY
Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA
Summary for 3CIY
Entry DOI | 10.2210/pdb3ciy/pdb |
Related | 2A0Z 3CIG |
Descriptor | 46-MER, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | leucine rich repeat, lrr, protein-dsrna complex, innate immunity, tlr, dsrna, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, immune system-rna complex, immune system/rna |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 197440.27 |
Authors | Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R. (deposition date: 2008-03-12, release date: 2008-05-06, Last modification date: 2023-08-30) |
Primary citation | Liu, L.,Botos, I.,Wang, Y.,Leonard, J.N.,Shiloach, J.,Segal, D.M.,Davies, D.R. Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science, 320:379-381, 2008 Cited by PubMed: 18420935DOI: 10.1126/science.1155406 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.41 Å) |
Structure validation
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