3CIY
Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | 46-MER | polymer | 46 | 14781.8 | 1 | |||
| 2 | B (D) | 46-MER | polymer | 46 | 14655.7 | 1 | |||
| 3 | C, D (A, B) | Toll-like receptor 3 | polymer | 697 | 79631.3 | 2 | UniProt (Q99MB1) Pfam (PF13855) Pfam (PF00560) | Mus musculus (house mouse) | CD283 antigen |
| 4 | E, H, L, O (E, H, L, O) | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G07375KG) | |||
| 5 | F (F) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 6 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 7 | I (I) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G21381MC) | |||
| 8 | J, Q (J, Q) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G35926TG) | |||
| 9 | K, R (K, R) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 10 | M (M) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 11 | N (N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G28454KX) | |||
| 12 | P (P) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G34198FQ) | |||
| 13 | S, T, U, V (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, B: 27 - 703 (UniProt: Q99MB1)
| PDB | External Database | Details |
|---|---|---|
| Asn 704 | - | expression tag |
| Leu 705 | - | expression tag |
| Tyr 706 | - | expression tag |
| Phe 707 | - | expression tag |
| Gln 708 | - | expression tag |
| Gly 709 | - | expression tag |
| His 710 | - | expression tag |
| His 711 | - | expression tag |
| His 712 | - | expression tag |
| His 713 | - | expression tag |
| His 714 | - | expression tag |
| His 715 | - | expression tag |
| Trp 716 | - | expression tag |
| Ser 717 | - | expression tag |
| His 718 | - | expression tag |
| Pro 719 | - | expression tag |
| Gln 720 | - | expression tag |
| Phe 721 | - | expression tag |
| Glu 722 | - | expression tag |
| Lys 723 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 188700.1 | |
| Branched | Number of molecules | 14 |
| Total formula weight | 7855.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 197440.3 |
